Pleuromutilin

Name: Pleuromutilin
Brand: Vaqora Chemicals
SKU: VQ-034212

About Pleuromutilin

Pleuromutilin is an impurity of Tiamulin carrying the CAS registry number 125-65-5. Formula C22H34O5, molecular weight 378.5 g/mol. It is also known as Drosophilin B or Mutilin 14-glycolate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Tiamulin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Pleuromutilin in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tiamulin

View every impurity, metabolite and intermediate we list for Tiamulin.

Tiamulin impurities

Specifications & identifiers

Chemical identifiers
Product name	Pleuromutilin
Catalogue No.	VQ-034212
CAS Number	125-65-5
IUPAC name	[(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl] 2-hydroxyacetate
Molecular formula	C₂₂H₃₄O₅
Molecular weight	378.5 g/mol
Exact mass	378.2406
Grade	Reference Standard
HSN code	38229090
InChIKey	ZRZNJUXESFHSIO-BKUNHTPHSA-N
SMILES	C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CO)C
PubChem CID	9886081

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	2 / 5
TPSA	83.8 Å²
Synonyms	Drosophilin B, Mutilin 14-glycolate, Pleuromuline, Antibiotic A 40104C, 14-Deoxy-14-((hydroxyacetyl)oxy)mutilin, BC-757, Drosopholin B, Glycolic acid, 8-ester with mutilin, BC 757, Antibiotic BC 757

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pleuromutilin?

The CAS Registry Number of Pleuromutilin is 125-65-5. It is also known as Drosophilin B, Mutilin 14-glycolate, Pleuromuline.

What is the molecular formula and molecular weight of Pleuromutilin?

Pleuromutilin has the molecular formula C22H34O5 and a molecular weight of 378.5 g/mol. Its IUPAC name is [(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl] 2-hydroxyacetate.

What is Pleuromutilin used for?

Pleuromutilin is supplied as a characterised reference material related to Tiamulin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pleuromutilin can I order?

We supply Pleuromutilin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pleuromutilin?

Yes. Every lot of Pleuromutilin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pleuromutilin be shipped internationally?

Yes. Pleuromutilin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.