Pazopanib metabolite M27

About Pazopanib metabolite M27

Pazopanib metabolite M27 is a metabolite or degradation product of Pazopanib carrying the CAS registry number 1252927-47-1. The compound has the formula C20H21N7O2S, corresponding to a molecular weight of 423.5 g/mol. The IUPAC name is 5-[[4-[(2,3-dimethylindazol-6-yl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide. Alternative names: N-Demethyl Pazopanib and Pazopanib N-Desmethyl Impurity.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Pazopanib, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Pazopanib

View every impurity, metabolite and intermediate we list for Pazopanib.

Pazopanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Pazopanib metabolite M27
Catalogue No.	VQ-033082
CAS Number	1252927-47-1
IUPAC name	5-[[4-[(2,3-dimethylindazol-6-yl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide
Molecular formula	C₂₀H₂₁N₇O₂S
Molecular weight	423.5 g/mol
Exact mass	423.1477
Grade	Reference Standard
HSN code	38229090
InChIKey	XWOGXAVHJKKNPO-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)NC3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
PubChem CID	68319455

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	3 / 8
TPSA	136 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pazopanib metabolite M27?

The CAS Registry Number of Pazopanib metabolite M27 is 1252927-47-1. It is also known as N-Demethyl Pazopanib, Pazopanib N-Desmethyl Impurity, Pazopanib Impurity 38.

What is the molecular formula and molecular weight of Pazopanib metabolite M27?

Pazopanib metabolite M27 has the molecular formula C20H21N7O2S and a molecular weight of 423.5 g/mol. Its IUPAC name is 5-[[4-[(2,3-dimethylindazol-6-yl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide.

What is Pazopanib metabolite M27 used for?

Pazopanib metabolite M27 is supplied as a characterised reference material related to Pazopanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pazopanib metabolite M27 can I order?

We supply Pazopanib metabolite M27 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pazopanib metabolite M27?

Yes. Every lot of Pazopanib metabolite M27 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pazopanib metabolite M27 be shipped internationally?

Yes. We export Pazopanib metabolite M27 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.