(R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)be… 1266664-66-7

Name: (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-051159

About (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride

(R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride is an impurity of Suvorexant carrying the CAS registry number 1266664-66-7. With the molecular formula C13H17Cl2N3O, it has a molar mass of 302.2 g/mol. Common synonyms include Suvorexant internate 3 and Suvorexant Intermediate V.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Suvorexant to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Suvorexant

View every impurity, metabolite and intermediate we list for Suvorexant.

Suvorexant impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride
Catalogue No.	VQ-051159
CAS Number	1266664-66-7
IUPAC name	5-chloro-2-[(5R)-5-methyl-1,4-diazepan-1-yl]-1,3-benzoxazole;hydrochloride
Molecular formula	C₁₃H₁₇Cl₂N₃O
Molecular weight	302.2 g/mol
Exact mass	301.0749
Grade	Reference Standard
HSN code	38229090
InChIKey	ZCQKTYRISREUFV-SBSPUUFOSA-N
SMILES	C[C@@H]1CCN(CCN1)C2=NC3=C(O2)C=CC(=C3)Cl.Cl
PubChem CID	60165609

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 4
TPSA	41.3 Å²
Synonyms	(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-ium chloride, 5-Chloro-2-((R)-5-Methyl-[1,4]diazepan-1-yl)benzooxazole hydrochloride, (R)-5-chloro-2-(5-methyl-[1,4]diazepan-1-yl)-benzoxazole hydrochloride, 5-Chloro-2-((R)-5-methyl-[1,4]diazepan-1-yl)-benzooxazole hydrochloride, 5-Chloro-2-[(5R)-hexahydro-5-methyl-1H-1,4-diazepin-1-yl]benzoxazole-hydrochloride, Suvorexant internate 3, Suvorexant Intermediate V, (R)-5-Chloro-2-(5-methyl-[1,4]diazepan-1-yl)-benzoxazole HCl, R-5-chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole HCl, (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzoxazole Hydrochloride

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H318Causes serious eye damage
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P264, P264 + P265, P270, P273, P280, P301 + P317, P305 + P354 + P338, P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride?

The CAS Registry Number of (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride is 1266664-66-7. It is also known as (7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-ium chloride, 5-Chloro-2-((R)-5-Methyl-[1,4]diazepan-1-yl)benzooxazole hydrochloride, (R)-5-chloro-2-(5-methyl-[1,4]diazepan-1-yl)-benzoxazole hydrochloride.

What is the molecular formula and molecular weight of (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride?

(R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride has the molecular formula C13H17Cl2N3O and a molecular weight of 302.2 g/mol.

What is (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride used for?

(R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride is supplied as a characterised reference material related to Suvorexant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride can I order?

We supply (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride?

Yes. Every lot of (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride be shipped internationally?

Yes. (R)-5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)benzo[d]oxazole hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.