(R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-… 126918-16-9

About (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one

(R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one is a metabolite or degradation product of Efinaconazole carrying the CAS registry number 126918-16-9. Its molecular formula is C9H8F2O2 and its molecular weight is 186.15 g/mol. Systematically, it is named (2R)-1-(2,4-difluorophenyl)-2-hydroxypropan-1-one. Common synonyms include (2R)-2',4'-difluoro-2-hydroxypropiophenone.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Efinaconazole, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Efinaconazole

View every impurity, metabolite and intermediate we list for Efinaconazole.

Efinaconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one
Catalogue No.	VQ-030392
CAS Number	126918-16-9
IUPAC name	(2R)-1-(2,4-difluorophenyl)-2-hydroxypropan-1-one
Molecular formula	C₉H₈F₂O₂
Molecular weight	186.15 g/mol
Exact mass	186.0492
Grade	Reference Standard
HSN code	38229090
InChIKey	REHMWFXPLWURSF-RXMQYKEDSA-N
SMILES	C[C@H](C(=O)C1=C(C=C(C=C1)F)F)O
PubChem CID	9794084

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 4
TPSA	37.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one?

The CAS Registry Number of (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one is 126918-16-9. It is also known as 1-Propanone, 1-(2,4-difluorophenyl)-2-hydroxy-, (2R)-, (R)-1-(2,4-Difluorophenyl)-2-hydroxy-1-propanone, (2R)-2',4'-difluoro-2-hydroxypropiophenone.

What is the molecular formula and molecular weight of (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one?

(R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one has the molecular formula C9H8F2O2 and a molecular weight of 186.15 g/mol. Its IUPAC name is (2R)-1-(2,4-difluorophenyl)-2-hydroxypropan-1-one.

What is (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one used for?

(R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one is supplied as a characterised reference material related to Efinaconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one can I order?

We supply (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one?

Yes. Every lot of (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one be shipped internationally?

Yes. We export (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.