1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1… 1269440-49-4

Name: 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one
Brand: Vaqora Chemicals
SKU: VQ-025539

About 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one

Listed under CAS 1269440-49-4, 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one is an impurity of Encorafenib available from Vaqora Chemicals. The compound has the formula C8H11IN2O, corresponding to a molecular weight of 278.09 g/mol. Systematically, it is named 1-(3-iodo-1-propan-2-ylpyrazol-4-yl)ethanone.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Encorafenib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Encorafenib

View every impurity, metabolite and intermediate we list for Encorafenib.

Encorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one
Catalogue No.	VQ-025539
CAS Number	1269440-49-4
IUPAC name	1-(3-iodo-1-propan-2-ylpyrazol-4-yl)ethanone
Molecular formula	C₈H₁₁IN₂O
Molecular weight	278.09 g/mol
Exact mass	277.9916
Grade	Reference Standard
HSN code	38229090
InChIKey	ALVXXWPPAVGXHP-UHFFFAOYSA-N
SMILES	CC(C)N1C=C(C(=N1)I)C(=O)C
PubChem CID	51034230

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	0 / 2
TPSA	34.9 Å²
Synonyms	1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethanone, 1-[3-Iodo-1-(1-methylethyl)-1H-pyrazol-4-yl]ethanone, 1-(3-Iodo-1-(1-methylethyl)-1H-pyrazol-4-yl)ethanone, 1-[3-iodo-1-(propan-2-yl)-1H-pyrazol-4-yl]ethan-1-one, Ethanone, 1-[3-iodo-1-(1-methylethyl)-1H-pyrazol-4-yl]-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one?

The CAS Registry Number of 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one is 1269440-49-4. It is also known as 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethanone, 1-[3-Iodo-1-(1-methylethyl)-1H-pyrazol-4-yl]ethanone, 1-(3-Iodo-1-(1-methylethyl)-1H-pyrazol-4-yl)ethanone.

What is the molecular formula and molecular weight of 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one?

1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one has the molecular formula C8H11IN2O and a molecular weight of 278.09 g/mol. Its IUPAC name is 1-(3-iodo-1-propan-2-ylpyrazol-4-yl)ethanone.

What is 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one used for?

1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one is supplied as a characterised reference material related to Encorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one can I order?

We supply 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one?

Yes. Every lot of 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one be shipped internationally?

Yes. 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethan-1-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.