11,12-Dehydroxy-Betamethasone

Name: 11,12-Dehydroxy-Betamethasone
Brand: Vaqora Chemicals
SKU: VQ-035953

About 11,12-Dehydroxy-Betamethasone

Vaqora Chemicals supplies 11,12-Dehydroxy-Betamethasone, an impurity of Betamethasone registered under CAS number 127034-59-7. Its molecular formula is C22H27FO4 and its molecular weight is 374.4 g/mol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Betamethasone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 11,12-Dehydroxy-Betamethasone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Betamethasone

View every impurity, metabolite and intermediate we list for Betamethasone.

Betamethasone impurities

Specifications & identifiers

Chemical identifiers
Product name	11,12-Dehydroxy-Betamethasone
Catalogue No.	VQ-035953
CAS Number	127034-59-7
IUPAC name	(8S,9R,10S,13S,14S,16S,17R)-9-fluoro-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,14,15,16-hexahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₂₇FO₄
Molecular weight	374.4 g/mol
Exact mass	374.1893
Grade	Reference Standard
HSN code	38229090
InChIKey	OETCKCTXJGBGQR-IVSIGIPOSA-N
SMILES	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3(C=C[C@@]2([C@]1(C(=O)CO)O)C)F)C
PubChem CID	70603422

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 5
TPSA	74.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 11,12-Dehydroxy-Betamethasone?

The CAS Registry Number of 11,12-Dehydroxy-Betamethasone is 127034-59-7. It is also known as 9-Fluoro-17a,21-dihydroxy-16b-methyl-pregna-1,4,11-triene-3,20-dione.

What is the molecular formula and molecular weight of 11,12-Dehydroxy-Betamethasone?

11,12-Dehydroxy-Betamethasone has the molecular formula C22H27FO4 and a molecular weight of 374.4 g/mol. Its IUPAC name is (8S,9R,10S,13S,14S,16S,17R)-9-fluoro-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,14,15,16-hexahydrocyclopenta[a]phenanthren-3-one.

What is 11,12-Dehydroxy-Betamethasone used for?

11,12-Dehydroxy-Betamethasone is supplied as a characterised reference material related to Betamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 11,12-Dehydroxy-Betamethasone can I order?

We supply 11,12-Dehydroxy-Betamethasone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 11,12-Dehydroxy-Betamethasone?

Yes. Every lot of 11,12-Dehydroxy-Betamethasone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 11,12-Dehydroxy-Betamethasone be shipped internationally?

Yes. We export 11,12-Dehydroxy-Betamethasone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.