Darifenacin Impurity B

About Darifenacin Impurity B

Darifenacin Impurity B is an impurity of Darifenacin carrying the CAS registry number 127264-14-6. The compound has the formula C10H11BrO, corresponding to a molecular weight of 227.1 g/mol. Its systematic (IUPAC) name is 5-(2-bromoethyl)-2,3-dihydro-1-benzofuran. Common synonyms include Darifenacin Bromo Impurity and 5-(2-Bromoethyl)-2,3-dihydrobenzofuran.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Darifenacin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Darifenacin

View every impurity, metabolite and intermediate we list for Darifenacin.

Darifenacin impurities

Specifications & identifiers

Chemical identifiers
Product name	Darifenacin Impurity B
Catalogue No.	VQ-025192
CAS Number	127264-14-6
IUPAC name	5-(2-bromoethyl)-2,3-dihydro-1-benzofuran
Molecular formula	C₁₀H₁₁BrO
Molecular weight	227.1 g/mol
Exact mass	225.9993
Grade	Reference Standard
HSN code	38229090
InChIKey	JRKZQRRYNCMSCB-UHFFFAOYSA-N
SMILES	C1COC2=C1C=C(C=C2)CCBr
PubChem CID	21831160

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	0 / 1
TPSA	9.2 Å²
Synonyms	Darifenacin Bromo Impurity, 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, Benzofuran, 5-(2-bromoethyl)-2,3-dihydro-, 5-(2-bromo-ethyl)-2,3-dihydro-benzofuran, 5-(2-bromoethyl)-2,3-dihydrobenzo[b]furan, 2-(2,3-Dihydrobenzfuran-5-yl)bromoethane, 5-(2-bromoethyl)-2,3-dihydrobenzo[2,3-b]furan, 5-(2-Bromoethyl)coumaran, 5-(2-bromoethyl) dihydrobenzofuran, CS-M0163, 5-(2-bromoethyl)-2,3dihydrobenzofuran, 5-(2-Bromethyl)-2,3-dihydrobenzofuran

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Darifenacin Impurity B?

The CAS Registry Number of Darifenacin Impurity B is 127264-14-6. It is also known as Darifenacin Bromo Impurity, 5-(2-Bromoethyl)-2,3-dihydrobenzofuran, Benzofuran, 5-(2-bromoethyl)-2,3-dihydro-.

What is the molecular formula and molecular weight of Darifenacin Impurity B?

Darifenacin Impurity B has the molecular formula C10H11BrO and a molecular weight of 227.1 g/mol. Its IUPAC name is 5-(2-bromoethyl)-2,3-dihydro-1-benzofuran.

What is Darifenacin Impurity B used for?

Darifenacin Impurity B is supplied as a characterised reference material related to Darifenacin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Darifenacin Impurity B can I order?

We supply Darifenacin Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Darifenacin Impurity B?

Yes. Every lot of Darifenacin Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Darifenacin Impurity B be shipped internationally?

Yes. Darifenacin Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.