Lansoprazole Chloromethyl Impurity

Name: Lansoprazole Chloromethyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-005129

About Lansoprazole Chloromethyl Impurity

Listed under CAS 127337-60-4, Lansoprazole Chloromethyl Impurity is an impurity of Lansoprazole available from Vaqora Chemicals. Its molecular formula is C9H10Cl2F3NO and its molecular weight is 276.08 g/mol. The IUPAC name is 2-(chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine. Hydrochloride. It is also known as Lansoprazole Intermediates.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Lansoprazole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Lansoprazole Chloromethyl Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lansoprazole

View every impurity, metabolite and intermediate we list for Lansoprazole.

Lansoprazole impurities

Specifications & identifiers

Chemical identifiers
Product name	Lansoprazole Chloromethyl Impurity
Catalogue No.	VQ-005129
CAS Number	127337-60-4
IUPAC name	2-(chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine;hydrochloride
Molecular formula	C₉H₁₀Cl₂F₃NO
Molecular weight	276.08 g/mol
Exact mass	275.0092
Grade	Reference Standard
HSN code	38229090
InChIKey	CMZBQUWICURDCD-UHFFFAOYSA-N
SMILES	CC1=C(C=CN=C1CCl)OCC(F)(F)F.Cl
PubChem CID	16217647

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 5
TPSA	22.1 Å²
Synonyms	2-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride, 2-(Chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride, Pyridine, 2-(chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)-, hydrochloride (1:1), 2-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine, Hydrochloride, 2-Chloromethyl-3-methyl-4-(2,2,2-trifluoro-ethoxy)-pyridine hydrochloride, 2-Chloromethyl-3-methyl-4-(2,2,2-trifluoro-ethoxy)-pyridine HCl, 2-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)-pyridine hydrochloride, 2-Chloromethyl-3-methyl-4-(2,2,2-trifluoro-ethoxy)pyridine Hydrochloride, 1-[2-(chloromethyl)-3-methyl(4-pyridyloxy)]-2,2,2-trifluoroethane, chloride, Lansoprazole Intermediates, 2-(Chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride (1:1), 2-(Chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine HCl

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H318Causes serious eye damage

Precautionary statements: P261, P264 + P265, P272, P280, P302 + P352, P305 + P354 + P338, P317, P321, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lansoprazole Chloromethyl Impurity?

The CAS Registry Number of Lansoprazole Chloromethyl Impurity is 127337-60-4. It is also known as 2-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride, 2-(Chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride, Pyridine, 2-(chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy)-, hydrochloride (1:1).

What is the molecular formula and molecular weight of Lansoprazole Chloromethyl Impurity?

Lansoprazole Chloromethyl Impurity has the molecular formula C9H10Cl2F3NO and a molecular weight of 276.08 g/mol.

What is Lansoprazole Chloromethyl Impurity used for?

Lansoprazole Chloromethyl Impurity is supplied as a characterised reference material related to Lansoprazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lansoprazole Chloromethyl Impurity can I order?

We supply Lansoprazole Chloromethyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lansoprazole Chloromethyl Impurity?

Yes. Every lot of Lansoprazole Chloromethyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lansoprazole Chloromethyl Impurity be shipped internationally?

Yes. Lansoprazole Chloromethyl Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.