4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((m… 127626-37-3

Name: 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-052041

About 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate

Listed under CAS 127626-37-3, 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate is a metabolite or degradation product of Doripenem available from Vaqora Chemicals. Formula C14H18N2O8S, molecular weight 374.37 g/mol. Its systematic (IUPAC) name is (4-nitrophenyl)methyl (2S,4R)-2-(hydroxymethyl)-4-methylsulfonyloxypyrrolidine-1-carboxylate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Doripenem, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Doripenem

View every impurity, metabolite and intermediate we list for Doripenem.

Doripenem impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate
Catalogue No.	VQ-052041
CAS Number	127626-37-3
IUPAC name	(4-nitrophenyl)methyl (2S,4R)-2-(hydroxymethyl)-4-methylsulfonyloxypyrrolidine-1-carboxylate
Molecular formula	C₁₄H₁₈N₂O₈S
Molecular weight	374.37 g/mol
Exact mass	374.0784
Grade	Reference Standard
HSN code	38229090
InChIKey	VEJXAWBFJHWZOI-QWHCGFSZSA-N
SMILES	CS(=O)(=O)O[C@@H]1C[C@H](N(C1)C(=O)OCC2=CC=C(C=C2)[N+](=O)[O-])CO
PubChem CID	16093852

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	1 / 8
TPSA	147 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate?

The CAS Registry Number of 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate is 127626-37-3. It is also known as (2S,4R)-4-nitrobenzyl 2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate, (2s,4r)-1-p-nitrobenzyloxycarbonyl-4-methanesulfonyloxypyrrolidine-2-methanol, (2S,trans)-4-Nitrobenzyl2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate.

What is the molecular formula and molecular weight of 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate?

4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate has the molecular formula C14H18N2O8S and a molecular weight of 374.37 g/mol. Its IUPAC name is (4-nitrophenyl)methyl (2S,4R)-2-(hydroxymethyl)-4-methylsulfonyloxypyrrolidine-1-carboxylate.

What is 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate used for?

4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate is supplied as a characterised reference material related to Doripenem. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate can I order?

We supply 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate?

Yes. Every lot of 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate be shipped internationally?

Yes. We export 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.