(1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrop… 1292836-20-4

About (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol

(1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol is an impurity of Pibrentasvir carrying the CAS registry number 1292836-20-4. The compound has the formula C16H12Cl2F2N2O6, corresponding to a molecular weight of 437.2 g/mol. Common synonyms include EX-A1969.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Pibrentasvir, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Pibrentasvir

View every impurity, metabolite and intermediate we list for Pibrentasvir.

Pibrentasvir impurities

Specifications & identifiers

Chemical identifiers
Product name	(1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol
Catalogue No.	VQ-041475
CAS Number	1292836-20-4
IUPAC name	(1S,4S)-1,4-bis(4-chloro-2-fluoro-5-nitrophenyl)butane-1,4-diol
Molecular formula	C₁₆H₁₂Cl₂F₂N₂O₆
Molecular weight	437.2 g/mol
Exact mass	436.004
Grade	Reference Standard
HSN code	38229090
InChIKey	CAXZNRBDCSSKBX-HOTGVXAUSA-N
SMILES	C1=C(C(=CC(=C1[N+](=O)[O-])Cl)F)[C@H](CC[C@@H](C2=CC(=C(C=C2F)Cl)[N+](=O)[O-])O)O
PubChem CID	58226846

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 8
TPSA	132 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol?

The CAS Registry Number of (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol is 1292836-20-4. It is also known as (1S,4S)-1,4-bis(4-chloro-2-fluoro-5-nitrophenyl)-1,4-butanediol, 1,4-Butanediol, 1,4-bis(4-chloro-2-fluoro-5-nitrophenyl)-, (1S,4S)-, EX-A1969.

What is the molecular formula and molecular weight of (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol?

(1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol has the molecular formula C16H12Cl2F2N2O6 and a molecular weight of 437.2 g/mol. Its IUPAC name is (1S,4S)-1,4-bis(4-chloro-2-fluoro-5-nitrophenyl)butane-1,4-diol.

What is (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol used for?

(1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol is supplied as a characterised reference material related to Pibrentasvir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol can I order?

We supply (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol?

Yes. Every lot of (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol be shipped internationally?

Yes. (1S, 4S) -1,4-bis (4-Chloro-2-fluoro-5-nitrophenyl) butane-1,4-diol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.