3-Acetyl-1H-pyrazole-5-carboxylic Acid

About 3-Acetyl-1H-pyrazole-5-carboxylic Acid

3-Acetyl-1H-pyrazole-5-carboxylic Acid is an impurity of Darolutamide carrying the CAS registry number 1297537-45-1. With the molecular formula C6H6N2O3, it has a molar mass of 154.12 g/mol. It is also known as 5-acetyl-1H-pyrazole-3-carboxylic acid or 1H-Pyrazole-3-carboxylic acid, 5-acetyl-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Darolutamide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3-Acetyl-1H-pyrazole-5-carboxylic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Darolutamide

View every impurity, metabolite and intermediate we list for Darolutamide.

Darolutamide impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Acetyl-1H-pyrazole-5-carboxylic Acid
Catalogue No.	VQ-036563
CAS Number	1297537-45-1
IUPAC name	3-acetyl-1H-pyrazole-5-carboxylic acid
Molecular formula	C₆H₆N₂O₃
Molecular weight	154.12 g/mol
Exact mass	154.0378
Grade	Reference Standard
HSN code	38229090
InChIKey	HFBWRCZRDIVAMQ-UHFFFAOYSA-N
SMILES	CC(=O)C1=NNC(=C1)C(=O)O
PubChem CID	16767346

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	2 / 4
TPSA	83.1 Å²
Synonyms	5-acetyl-1H-pyrazole-3-carboxylic acid, 1H-Pyrazole-3-carboxylic acid, 5-acetyl-, 5-acetylpyrazole-3-carboxylic acid, 1H-pyrazole-5-carboxylic acid, 3-acetyl-, 5-acetyl, 5-acetyl-2H-pyrazole-3-carboxylic acid, 5-acetyl-1H-pyrazole-3-carboxylicacid, 3-Acetyl-1H-pyrazole-5-carboxylic acid, AldrichCPR

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Acetyl-1H-pyrazole-5-carboxylic Acid?

The CAS Registry Number of 3-Acetyl-1H-pyrazole-5-carboxylic Acid is 1297537-45-1. It is also known as 5-acetyl-1H-pyrazole-3-carboxylic acid, 1H-Pyrazole-3-carboxylic acid, 5-acetyl-, 5-acetylpyrazole-3-carboxylic acid.

What is the molecular formula and molecular weight of 3-Acetyl-1H-pyrazole-5-carboxylic Acid?

3-Acetyl-1H-pyrazole-5-carboxylic Acid has the molecular formula C6H6N2O3 and a molecular weight of 154.12 g/mol. Its IUPAC name is 3-acetyl-1H-pyrazole-5-carboxylic acid.

What is 3-Acetyl-1H-pyrazole-5-carboxylic Acid used for?

3-Acetyl-1H-pyrazole-5-carboxylic Acid is supplied as a characterised reference material related to Darolutamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Acetyl-1H-pyrazole-5-carboxylic Acid can I order?

We supply 3-Acetyl-1H-pyrazole-5-carboxylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Acetyl-1H-pyrazole-5-carboxylic Acid?

Yes. Every lot of 3-Acetyl-1H-pyrazole-5-carboxylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Acetyl-1H-pyrazole-5-carboxylic Acid be shipped internationally?

Yes. 3-Acetyl-1H-pyrazole-5-carboxylic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.