(2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidineca… 129797-28-0

About (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid

(2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid is an impurity of Migalastat carrying the CAS registry number 129797-28-0. Formula C6H11NO5, molecular weight 177.16 g/mol. Its systematic (IUPAC) name is (2S,3S,4R,5S)-3,4,5-trihydroxypiperidine-2-carboxylic acid. It is also known as (2S,3S,4R,5S)-3,4,5-trihydroxypipecolicacid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Migalastat to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Migalastat

View every impurity, metabolite and intermediate we list for Migalastat.

Migalastat impurities

Specifications & identifiers

Chemical identifiers
Product name	(2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid
Catalogue No.	VQ-035318
CAS Number	129797-28-0
IUPAC name	(2S,3S,4R,5S)-3,4,5-trihydroxypiperidine-2-carboxylic acid
Molecular formula	C₆H₁₁NO₅
Molecular weight	177.16 g/mol
Exact mass	177.0637
Grade	Reference Standard
HSN code	38229090
InChIKey	ZHFMVVUVCALAMY-KLVWXMOXSA-N
SMILES	C1[C@@H]([C@H]([C@H]([C@H](N1)C(=O)O)O)O)O
PubChem CID	11008471

Physical properties
Physical form	Solid
LogP (XLogP3)	-4.4
H-bond donors / acceptors	5 / 6
TPSA	110 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid?

The CAS Registry Number of (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid is 129797-28-0. It is also known as (2S,3S,4R,5S)-3,4,5-trihydroxypipecolicacid, 2-Piperidinecarboxylic acid, 3,4,5-trihydroxy-, (2S,3S,4R,5S)-, 2-Piperidinecarboxylic acid, 3,4,5-trihydroxy-, [2S-(2alpha,3alpha,4alpha,5beta)]-.

What is the molecular formula and molecular weight of (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid?

(2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid has the molecular formula C6H11NO5 and a molecular weight of 177.16 g/mol. Its IUPAC name is (2S,3S,4R,5S)-3,4,5-trihydroxypiperidine-2-carboxylic acid.

What is (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid used for?

(2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid is supplied as a characterised reference material related to Migalastat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid can I order?

We supply (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid?

Yes. Every lot of (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid be shipped internationally?

Yes. We export (2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.