Levocetirizine dihydrochloride

Name: Levocetirizine dihydrochloride
Brand: Vaqora Chemicals
SKU: VQ-007540

About Levocetirizine dihydrochloride

Levocetirizine dihydrochloride (CAS 130018-87-0) is a high-purity reference standard of Levocetirizine offered by Vaqora Chemicals. Formula C21H27Cl3N2O3, molecular weight 461.8 g/mol. Its systematic (IUPAC) name is 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid. Dihydrochloride. Alternative names: (R)-Cetirizine dihydrochloride and Xyzal.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Levocetirizine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Levocetirizine dihydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Levocetirizine

View every impurity, metabolite and intermediate we list for Levocetirizine.

Levocetirizine impurities

Specifications & identifiers

Chemical identifiers
Product name	Levocetirizine dihydrochloride
Catalogue No.	VQ-007540
CAS Number	130018-87-0
IUPAC name	2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid;dihydrochloride
Molecular formula	C₂₁H₂₇Cl₃N₂O₃
Molecular weight	461.8 g/mol
Exact mass	460.1087
Grade	Reference Standard
HSN code	38229090
InChIKey	PGLIUCLTXOYQMV-GHVWMZMZSA-N
SMILES	C1CN(CCN1CCOCC(=O)O)[C@H](C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
PubChem CID	9955977

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 5
TPSA	53 Å²
Synonyms	(R)-Cetirizine dihydrochloride, Xyzal, Xyzal Allergy 24hr, Childrens Xyzal Allergy, good sense levocetirizine, cetirizine (R)-form dihydrochloride, (2-(4-((R)-(4-Chlorophenyl)phenylmethyl)piperazin-1-yl)ethoxy)acetic acid dihydrochloride, (2-{4-[(R)-(4-Chlorophenyl)phenylmethyl]piperazin-1-yl}ethoxy)acetic acid dihydrochloride, Allery Relief 24HR, Allergy Relief 24HR, Levocetirizine dihydrochloride 5 mg, Levocetirizine 2HCl

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H400Very toxic to aquatic life

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levocetirizine dihydrochloride?

The CAS Registry Number of Levocetirizine dihydrochloride is 130018-87-0. It is also known as (R)-Cetirizine dihydrochloride, Xyzal, Xyzal Allergy 24hr.

What is the molecular formula and molecular weight of Levocetirizine dihydrochloride?

Levocetirizine dihydrochloride has the molecular formula C21H27Cl3N2O3 and a molecular weight of 461.8 g/mol.

What is Levocetirizine dihydrochloride used for?

Levocetirizine dihydrochloride is supplied as a characterised reference material related to Levocetirizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levocetirizine dihydrochloride can I order?

We supply Levocetirizine dihydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levocetirizine dihydrochloride?

Yes. Every lot of Levocetirizine dihydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levocetirizine dihydrochloride be shipped internationally?

Yes. Levocetirizine dihydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.