(8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydro… 131918-73-5

About (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one

(8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one is a metabolite or degradation product of Budesonide carrying the CAS registry number 131918-73-5. Its molecular formula is C21H26O6 and its molecular weight is 374.4 g/mol. Alternative names: 14,15-Dehydro-16 a-hydroxyprednisolone.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Budesonide, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Budesonide

View every impurity, metabolite and intermediate we list for Budesonide.

Budesonide impurities

Specifications & identifiers

Chemical identifiers
Product name	(8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.	VQ-021916
CAS Number	131918-73-5
IUPAC name	(8R,9S,10R,11S,13S,16R,17S)-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,16-hexahydro-6H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₁H₂₆O₆
Molecular weight	374.4 g/mol
Exact mass	374.1729
Grade	Reference Standard
HSN code	38229090
InChIKey	DIGGLNJQCGHXQV-XUPWNSBFSA-N
SMILES	C[C@]12C[C@@H]([C@H]3[C@H](C1=C[C@H]([C@@]2(C(=O)CO)O)O)CCC4=CC(=O)C=C[C@]34C)O
PubChem CID	67906358

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	4 / 6
TPSA	115 Å²
Synonyms	11beta,16alpha,17,21-Tetrahydroxy-pregna-1,4,14-triene-3,20-dione, 14,15-Dehydro-16 a-hydroxyprednisolone, 11, A,16, A,17,21-Tetrahydroxy-pregna-1,4,14-triene-3,20-dione

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one?

The CAS Registry Number of (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one is 131918-73-5. It is also known as 11beta,16alpha,17,21-Tetrahydroxy-pregna-1,4,14-triene-3,20-dione, 14,15-Dehydro-16 a-hydroxyprednisolone, 11.

What is the molecular formula and molecular weight of (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one?

(8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one has the molecular formula C21H26O6 and a molecular weight of 374.4 g/mol. Its IUPAC name is (8R,9S,10R,11S,13S,16R,17S)-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,16-hexahydro-6H-cyclopenta[a]phenanthren-3-one.

What is (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one used for?

(8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one is supplied as a characterised reference material related to Budesonide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one can I order?

We supply (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one?

Yes. Every lot of (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one be shipped internationally?

Yes. We export (8R,9S,10R,11S,13S,16R,17S)-11,16,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.