N-Methyl Duloxetine

Name: N-Methyl Duloxetine
Brand: Vaqora Chemicals
SKU: VQ-030336

About N-Methyl Duloxetine

Vaqora Chemicals supplies N-Methyl Duloxetine, an impurity of Duloxetine registered under CAS number 132335-46-7. With the molecular formula C19H21NOS, it has a molar mass of 311.4 g/mol. The IUPAC name is (3S)-N,N-dimethyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine. Common synonyms include N-Methyl Duloxetine Oxalate and Duloxetine N-Methyl.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Duloxetine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Methyl Duloxetine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Methyl Duloxetine
Catalogue No.	VQ-030336
CAS Number	132335-46-7
IUPAC name	(3S)-N,N-dimethyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine
Molecular formula	C₁₉H₂₁NOS
Molecular weight	311.4 g/mol
Exact mass	311.1344
Grade	Reference Standard
HSN code	38229090
InChIKey	JFTURWWGPMTABQ-SFHVURJKSA-N
SMILES	CN(C)CC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32
PubChem CID	9818212

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	0 / 3
TPSA	40.7 Å²
Synonyms	N-Methyl Duloxetine Oxalate, (S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine, (S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, 2-Thiophenepropanamine, N,N-dimethyl-gamma-(1-naphthalenyloxy)-, (gammaS)-, Duloxetine N-Methyl, N-Methyl-(S)-duloxetine, (S)-N,N-dimethyl-3-(naphthyloxy)-3-(2-thienyl)propylamine, (S)-N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)-propanamine, (gammaS)-N,N-Dimethyl-gamma-(1-naphthalenyloxy)-2-thiophenepropanamine, (S)-(+) -N, N-dimethyl -3- (1-naphthalenyloxy)-3-(2-thienyl)propanamine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Methyl Duloxetine?

The CAS Registry Number of N-Methyl Duloxetine is 132335-46-7. It is also known as N-Methyl Duloxetine Oxalate, (S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine, (S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine.

What is the molecular formula and molecular weight of N-Methyl Duloxetine?

N-Methyl Duloxetine has the molecular formula C19H21NOS and a molecular weight of 311.4 g/mol. Its IUPAC name is (3S)-N,N-dimethyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine.

What is N-Methyl Duloxetine used for?

N-Methyl Duloxetine is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Methyl Duloxetine can I order?

We supply N-Methyl Duloxetine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Methyl Duloxetine?

Yes. Every lot of N-Methyl Duloxetine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Methyl Duloxetine be shipped internationally?

Yes. We export N-Methyl Duloxetine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.