2-Amino-5-chlorobenzene sulfonic acid

About 2-Amino-5-chlorobenzene sulfonic acid

2-Amino-5-chlorobenzene sulfonic acid is an impurity of Diazoxide carrying the CAS registry number 133-74-4. With the molecular formula C6H6ClNO3S, it has a molar mass of 207.64 g/mol. Common synonyms include 2-Amino-5-chlorobenzenesulphonic acid and 5-Chloroorthanilic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Diazoxide, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Diazoxide

View every impurity, metabolite and intermediate we list for Diazoxide.

Diazoxide impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Amino-5-chlorobenzene sulfonic acid
Catalogue No.	VQ-023410
CAS Number	133-74-4
IUPAC name	2-amino-5-chlorobenzenesulfonic acid
Molecular formula	C₆H₆ClNO₃S
Molecular weight	207.64 g/mol
Exact mass	206.9757
Grade	Reference Standard
HSN code	38229090
InChIKey	ZCGVPUAAMCMLTM-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1Cl)S(=O)(=O)O)N
PubChem CID	8628

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	2 / 4
TPSA	88.8 Å²
Synonyms	2-Amino-5-chlorobenzenesulphonic acid, 5-Chloroorthanilic acid, Benzenesulfonic acid, 2-amino-5-chloro-, 2-amino-5-chlorobenzene-1-sulfonic acid, p-Chloranilin-o-sulfosaure, 2-amino-5-chl, p-Chloroaniline-o-sulfonic acid, 1-Amino-4-chloro-2-benzenesulfonic acid

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P264 + P265, P271, P280, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P319, P321, P332 + P317, P337 + P317, P362 + P364, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Amino-5-chlorobenzene sulfonic acid?

The CAS Registry Number of 2-Amino-5-chlorobenzene sulfonic acid is 133-74-4. It is also known as 2-Amino-5-chlorobenzenesulphonic acid, 5-Chloroorthanilic acid, Benzenesulfonic acid, 2-amino-5-chloro-.

What is the molecular formula and molecular weight of 2-Amino-5-chlorobenzene sulfonic acid?

2-Amino-5-chlorobenzene sulfonic acid has the molecular formula C6H6ClNO3S and a molecular weight of 207.64 g/mol. Its IUPAC name is 2-amino-5-chlorobenzenesulfonic acid.

What is 2-Amino-5-chlorobenzene sulfonic acid used for?

2-Amino-5-chlorobenzene sulfonic acid is supplied as a characterised reference material related to Diazoxide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Amino-5-chlorobenzene sulfonic acid can I order?

We supply 2-Amino-5-chlorobenzene sulfonic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Amino-5-chlorobenzene sulfonic acid?

Yes. Every lot of 2-Amino-5-chlorobenzene sulfonic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Amino-5-chlorobenzene sulfonic acid be shipped internationally?

Yes. 2-Amino-5-chlorobenzene sulfonic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.