(R)-1-Tosylpyrrolidin-3-ol

Name: (R)-1-Tosylpyrrolidin-3-ol
Brand: Vaqora Chemicals
SKU: VQ-047945

About (R)-1-Tosylpyrrolidin-3-ol

Vaqora Chemicals supplies (R)-1-Tosylpyrrolidin-3-ol, a process intermediate or related compound of Darifenacin registered under CAS number 133034-00-1. Formula C11H15NO3S, molecular weight 241.31 g/mol. Systematically, it is named (3R)-1-(4-methylphenyl)sulfonylpyrrolidin-3-ol. It is also known as 1-(p-Tosyl)-(R)-(-)-3-pyrrolidinol or 1-tosyl-3-(R)-(-)-hydroxypyrrolidine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Darifenacin, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer (R)-1-Tosylpyrrolidin-3-ol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Darifenacin

View every impurity, metabolite and intermediate we list for Darifenacin.

Darifenacin impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-1-Tosylpyrrolidin-3-ol
Catalogue No.	VQ-047945
CAS Number	133034-00-1
IUPAC name	(3R)-1-(4-methylphenyl)sulfonylpyrrolidin-3-ol
Molecular formula	C₁₁H₁₅NO₃S
Molecular weight	241.31 g/mol
Exact mass	241.0773
HSN code	2933
InChIKey	GOIRRXGVYYWCGC-SNVBAGLBSA-N
SMILES	CC1=CC=C(C=C1)S(=O)(=O)N2CC[C@H](C2)O
PubChem CID	16216944

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	1 / 4
TPSA	66 Å²
Synonyms	1-(p-Tosyl)-(R)-(-)-3-pyrrolidinol, (3R)-1-[(4-methylphenyl)sulfonyl]tetrahydro-1H-pyrrol-3-ol, (3R)-1-(4-methylbenzenesulfonyl)pyrrolidin-3-ol, (3R)-1-[(4-Methylphenyl)sulfonyl]-3-pyrrolidinol, 1-tosyl-3-(R)-(-)-hydroxypyrrolidine, (3R)-1-(p-tolylsulfonyl)pyrrolidin-3-ol, (3R)-1-(4-Methylbenzene-1-sulfonyl)pyrrolidin-3-ol, 3-Pyrrolidinol, 1-[(4-methylphenyl)sulfonyl]-, (3R)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-1-Tosylpyrrolidin-3-ol?

The CAS Registry Number of (R)-1-Tosylpyrrolidin-3-ol is 133034-00-1. It is also known as 1-(p-Tosyl)-(R)-(-)-3-pyrrolidinol, (3R)-1-[(4-methylphenyl)sulfonyl]tetrahydro-1H-pyrrol-3-ol, (3R)-1-(4-methylbenzenesulfonyl)pyrrolidin-3-ol.

What is the molecular formula and molecular weight of (R)-1-Tosylpyrrolidin-3-ol?

(R)-1-Tosylpyrrolidin-3-ol has the molecular formula C11H15NO3S and a molecular weight of 241.31 g/mol. Its IUPAC name is (3R)-1-(4-methylphenyl)sulfonylpyrrolidin-3-ol.

What is (R)-1-Tosylpyrrolidin-3-ol used for?

(R)-1-Tosylpyrrolidin-3-ol is supplied as a characterised reference material related to Darifenacin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-1-Tosylpyrrolidin-3-ol can I order?

We supply (R)-1-Tosylpyrrolidin-3-ol, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-1-Tosylpyrrolidin-3-ol?

Yes. Every lot of (R)-1-Tosylpyrrolidin-3-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-1-Tosylpyrrolidin-3-ol be shipped internationally?

Yes. (R)-1-Tosylpyrrolidin-3-ol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.