2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydr… 13338-49-3

About 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride

2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride is an impurity of Phentolamine carrying the CAS registry number 13338-49-3. With the molecular formula C4H8Cl2N2, it has a molar mass of 155.02 g/mol. Alternative names: chlormethylimidazoline hydrochloride and 2-chloromethyl-2-imidazoline hydrochloride.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Phentolamine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Phentolamine

View every impurity, metabolite and intermediate we list for Phentolamine.

Phentolamine impurities

Specifications & identifiers

Chemical identifiers
Product name	2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride
Catalogue No.	VQ-027464
CAS Number	13338-49-3
IUPAC name	2-(chloromethyl)-4,5-dihydro-1H-imidazole;hydrochloride
Molecular formula	C₄H₈Cl₂N₂
Molecular weight	155.02 g/mol
Exact mass	154.0065
Grade	Reference Standard
HSN code	38229090
InChIKey	GHCCHMFFNHOXEU-UHFFFAOYSA-N
SMILES	C1CN=C(N1)CCl.Cl
PubChem CID	2760928

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 1
TPSA	24.4 Å²
Synonyms	chlormethylimidazoline hydrochloride, 1H-Imidazole, 2-(chloromethyl)-4,5-dihydro-, hydrochloride (1:1), 2-chloromethyl-2-imidazoline hydrochloride, 1H-Imidazole, 2-(chloromethyl)-4,5-dihydro-, monohydrochloride, 2-(chloromethyl)imidazoline hydrochloride, 2-(Chloromethyl)-4,5-dihydroimidazole Hydrochloride, 2-chloromethylimidazoline-hydrochloride, 2-(Chloromethyl)-4,5-dihydro-1H-imidazole hydrochloride (1:1)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride?

The CAS Registry Number of 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride is 13338-49-3. It is also known as chlormethylimidazoline hydrochloride, 1H-Imidazole, 2-(chloromethyl)-4,5-dihydro-, hydrochloride (1:1), 2-chloromethyl-2-imidazoline hydrochloride.

What is the molecular formula and molecular weight of 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride?

2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride has the molecular formula C4H8Cl2N2 and a molecular weight of 155.02 g/mol.

What is 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride used for?

2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride is supplied as a characterised reference material related to Phentolamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride can I order?

We supply 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride?

Yes. Every lot of 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride be shipped internationally?

Yes. 2-(Chloromethyl)-4,5-dihydro-1H-imidazolehydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.