12-Hydroxy Nevirapine

Name: 12-Hydroxy Nevirapine
Brand: Vaqora Chemicals
SKU: VQ-038599

About 12-Hydroxy Nevirapine

12-Hydroxy Nevirapine is a metabolite or degradation product of Nevirapine carrying the CAS registry number 133627-24-4. The compound has the formula C15H14N4O2, corresponding to a molecular weight of 282.3 g/mol. The IUPAC name is 2-cyclopropyl-7-(hydroxymethyl)-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one. It is also known as 12-hydroxy-NVP or 12-OH-NVP.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Nevirapine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 12-Hydroxy Nevirapine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Nevirapine

View every impurity, metabolite and intermediate we list for Nevirapine.

Nevirapine impurities

Specifications & identifiers

Chemical identifiers
Product name	12-Hydroxy Nevirapine
Catalogue No.	VQ-038599
CAS Number	133627-24-4
IUPAC name	2-cyclopropyl-7-(hydroxymethyl)-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
Molecular formula	C₁₅H₁₄N₄O₂
Molecular weight	282.3 g/mol
Exact mass	282.1117
Grade	Reference Standard
HSN code	38229090
InChIKey	SEBABOMFNCVZGF-UHFFFAOYSA-N
SMILES	C1CC1N2C3=C(C=CC=N3)C(=O)NC4=C(C=CN=C42)CO
PubChem CID	453338

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	2 / 5
TPSA	78.4 Å²
Synonyms	12-hydroxy-NVP, N11-Cyclopropyl-4-hydroxymethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one, N11-Cyclopropyl-4-hydroxymethyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 12-OH-NVP, Nevirapin 4-substituted deriv. 2, 11-cyclopropyl-4-(hydroxymethyl)-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one, 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2,3-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-hydroxymethyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, N(11)-cyclopropyl-4-hydroxymethyl-5,11-dihydro-6H-dipyrido(3,2-b:2,3-e)(1,4)diazepin-6-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 12-Hydroxy Nevirapine?

The CAS Registry Number of 12-Hydroxy Nevirapine is 133627-24-4. It is also known as 12-hydroxy-NVP, N11-Cyclopropyl-4-hydroxymethyl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one, N11-Cyclopropyl-4-hydroxymethyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one.

What is the molecular formula and molecular weight of 12-Hydroxy Nevirapine?

12-Hydroxy Nevirapine has the molecular formula C15H14N4O2 and a molecular weight of 282.3 g/mol. Its IUPAC name is 2-cyclopropyl-7-(hydroxymethyl)-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one.

What is 12-Hydroxy Nevirapine used for?

12-Hydroxy Nevirapine is supplied as a characterised reference material related to Nevirapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 12-Hydroxy Nevirapine can I order?

We supply 12-Hydroxy Nevirapine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 12-Hydroxy Nevirapine?

Yes. Every lot of 12-Hydroxy Nevirapine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 12-Hydroxy Nevirapine be shipped internationally?

Yes. We export 12-Hydroxy Nevirapine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.