2-Chloro-N4-isobutylquinoline-3,4-diamine

Name: 2-Chloro-N4-isobutylquinoline-3,4-diamine
Brand: Vaqora Chemicals
SKU: VQ-012948

About 2-Chloro-N4-isobutylquinoline-3,4-diamine

Listed under CAS 133860-76-1, 2-Chloro-N4-isobutylquinoline-3,4-diamine is a process intermediate or related compound of Imiquimod available from Vaqora Chemicals at a purity of 97%. With the molecular formula C13H16ClN3, it has a molar mass of 249.74 g/mol. The IUPAC name is 2-chloro-4-N-(2-methylpropyl)quinoline-3,4-diamine. Alternative names: 2-Chloro-3-Amino-4-Isobutylaminoquinoline.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Imiquimod, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 2-Chloro-N4-isobutylquinoline-3,4-diamine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Imiquimod

View every impurity, metabolite and intermediate we list for Imiquimod.

Imiquimod impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Chloro-N4-isobutylquinoline-3,4-diamine
Catalogue No.	VQ-012948
CAS Number	133860-76-1
IUPAC name	2-chloro-4-N-(2-methylpropyl)quinoline-3,4-diamine
Molecular formula	C₁₃H₁₆ClN₃
Molecular weight	249.74 g/mol
Exact mass	249.1033
Grade	Reference Standard
Purity / assay	97%
HSN code	2933
InChIKey	JARNINMUMFRNPS-UHFFFAOYSA-N
SMILES	CC(C)CNC1=C(C(=NC2=CC=CC=C21)Cl)N
PubChem CID	11747039

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	2 / 3
TPSA	50.9 Å²
Synonyms	2-Chloro-N4-(2-methylpropyl)-3,4-quinolinediamine, 2-Chloro-3-Amino-4-Isobutylaminoquinoline, 2-Chloro-N'-(2-methylpropyl)quinoline-3,4-diamine, 2-Chloro-N4-isobutylquinoline-3,4-diamine, 2-chloro-3-amino-4-(2-methylpropylamino)quinoline, 2-Chloro-N4-(2-methypropyl)-3,4-quinolinediamine, 3-amino-2-chloro-4-[(2-methylpropyl)amino]quinoline, 3,4-Quinolinediamine, 2-chloro-N4-(2-methylpropyl)-, 2-chloro-3-amino-4-[N-(2-methylpropyl)]amino quinoline, 2-chloro-N4-(2-methylpropyl)quinoline-3,4-diamine, 3,4-Quinolinediamine,2-chloro-N4-(2-methylpropyl)-, 2-Chloro-N~4~-(2-methylpropyl)quinoline-3,4-diamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chloro-N4-isobutylquinoline-3,4-diamine?

The CAS Registry Number of 2-Chloro-N4-isobutylquinoline-3,4-diamine is 133860-76-1. It is also known as 2-Chloro-N4-(2-methylpropyl)-3,4-quinolinediamine, 2-Chloro-3-Amino-4-Isobutylaminoquinoline, 2-Chloro-N'-(2-methylpropyl)quinoline-3,4-diamine.

What is the molecular formula and molecular weight of 2-Chloro-N4-isobutylquinoline-3,4-diamine?

2-Chloro-N4-isobutylquinoline-3,4-diamine has the molecular formula C13H16ClN3 and a molecular weight of 249.74 g/mol. Its IUPAC name is 2-chloro-4-N-(2-methylpropyl)quinoline-3,4-diamine.

What is 2-Chloro-N4-isobutylquinoline-3,4-diamine used for?

2-Chloro-N4-isobutylquinoline-3,4-diamine is supplied as a characterised reference material related to Imiquimod. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Chloro-N4-isobutylquinoline-3,4-diamine can I order?

We supply 2-Chloro-N4-isobutylquinoline-3,4-diamine in Reference Standard (97%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chloro-N4-isobutylquinoline-3,4-diamine?

Yes. Every lot of 2-Chloro-N4-isobutylquinoline-3,4-diamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chloro-N4-isobutylquinoline-3,4-diamine be shipped internationally?

Yes. 2-Chloro-N4-isobutylquinoline-3,4-diamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.