Bupivacaine N-oxide

Name: Bupivacaine N-oxide
Brand: Vaqora Chemicals
SKU: VQ-024685

About Bupivacaine N-oxide

Bupivacaine N-oxide (CAS 1346597-81-6) is a metabolite or degradation product of Bupivacaine offered by Vaqora Chemicals. The compound has the formula C18H28N2O2, corresponding to a molecular weight of 304.4 g/mol. Systematically, it is named 1-butyl-N-(2,6-dimethylphenyl)-1-oxidopiperidin-1-ium-2-carboxamide. Common synonyms include Bupivacaine N-Oxide HCl and Buvacaine N-Oxide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Bupivacaine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Bupivacaine N-oxide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bupivacaine

View every impurity, metabolite and intermediate we list for Bupivacaine.

Bupivacaine impurities

Specifications & identifiers

Chemical identifiers
Product name	Bupivacaine N-oxide
Catalogue No.	VQ-024685
CAS Number	1346597-81-6
IUPAC name	1-butyl-N-(2,6-dimethylphenyl)-1-oxidopiperidin-1-ium-2-carboxamide
Molecular formula	C₁₈H₂₈N₂O₂
Molecular weight	304.4 g/mol
Exact mass	304.2151
Grade	Reference Standard
HSN code	38229090
InChIKey	XZMRWWGDLLHXQD-UHFFFAOYSA-N
SMILES	CCCC[N+]1(CCCCC1C(=O)NC2=C(C=CC=C2C)C)[O-]
PubChem CID	71314303

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	1 / 2
TPSA	47.2 Å²
Synonyms	Bupivacaine N-Oxide HCl, 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, 1-oxide, Buvacaine N-Oxide, 1-butyl-2-((2,6-dimethylphenyl)carbamoyl)piperidine 1-oxide, 1-Butyl-N-(2,6-dimethylphenyl)-1-oxo-1lambda~5~-piperidine-2-carboxamide

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bupivacaine N-oxide?

The CAS Registry Number of Bupivacaine N-oxide is 1346597-81-6. It is also known as Bupivacaine N-Oxide HCl, 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, 1-oxide, Buvacaine N-Oxide.

What is the molecular formula and molecular weight of Bupivacaine N-oxide?

Bupivacaine N-oxide has the molecular formula C18H28N2O2 and a molecular weight of 304.4 g/mol. Its IUPAC name is 1-butyl-N-(2,6-dimethylphenyl)-1-oxidopiperidin-1-ium-2-carboxamide.

What is Bupivacaine N-oxide used for?

Bupivacaine N-oxide is supplied as a characterised reference material related to Bupivacaine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bupivacaine N-oxide can I order?

We supply Bupivacaine N-oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bupivacaine N-oxide?

Yes. Every lot of Bupivacaine N-oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bupivacaine N-oxide be shipped internationally?

Yes. Bupivacaine N-oxide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.