Azelastine N-Oxide (R)-Isomer

Name: Azelastine N-Oxide (R)-Isomer
Brand: Vaqora Chemicals
SKU: VQ-028916

About Azelastine N-Oxide (R)-Isomer

Listed under CAS 1346617-18-2, Azelastine N-Oxide (R)-Isomer is a metabolite or degradation product of Azelastine available from Vaqora Chemicals. The compound has the formula C22H24ClN3O2, corresponding to a molecular weight of 397.9 g/mol. Its systematic (IUPAC) name is 4-[(4-chlorophenyl)methyl]-2-[(4R)-1-methyl-1-oxidoazepan-1-ium-4-yl]phthalazin-1-one. Alternative names: (R)-Azelastine N-Oxide and (R)-AzelastineN-Oxide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Azelastine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Azelastine

View every impurity, metabolite and intermediate we list for Azelastine.

Azelastine impurities

Specifications & identifiers

Chemical identifiers
Product name	Azelastine N-Oxide (R)-Isomer
Catalogue No.	VQ-028916
CAS Number	1346617-18-2
IUPAC name	4-[(4-chlorophenyl)methyl]-2-[(4R)-1-methyl-1-oxidoazepan-1-ium-4-yl]phthalazin-1-one
Molecular formula	C₂₂H₂₄ClN₃O₂
Molecular weight	397.9 g/mol
Exact mass	397.1557
Grade	Reference Standard
HSN code	38229090
InChIKey	QFWLGALGCDUDAP-QOBPCVTDSA-N
SMILES	C[N+]1(CCC[C@H](CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl)[O-]
PubChem CID	71313563

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	0 / 3
TPSA	50.7 Å²
Synonyms	(R)-Azelastine N-Oxide (Mixture of Diastereomers), (R)-Azelastine N-Oxide, (4R)-4-(4-(4-Chlorobenzyl)-1-oxophthalazin-2(1H)-yl)-1-methylazepane 1-oxide, (R)-AzelastineN-Oxide, AzelastineN-Oxide, (R)-

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Azelastine N-Oxide (R)-Isomer?

The CAS Registry Number of Azelastine N-Oxide (R)-Isomer is 1346617-18-2. It is also known as (R)-Azelastine N-Oxide (Mixture of Diastereomers), (R)-Azelastine N-Oxide, (4R)-4-(4-(4-Chlorobenzyl)-1-oxophthalazin-2(1H)-yl)-1-methylazepane 1-oxide.

What is the molecular formula and molecular weight of Azelastine N-Oxide (R)-Isomer?

Azelastine N-Oxide (R)-Isomer has the molecular formula C22H24ClN3O2 and a molecular weight of 397.9 g/mol. Its IUPAC name is 4-[(4-chlorophenyl)methyl]-2-[(4R)-1-methyl-1-oxidoazepan-1-ium-4-yl]phthalazin-1-one.

What is Azelastine N-Oxide (R)-Isomer used for?

Azelastine N-Oxide (R)-Isomer is supplied as a characterised reference material related to Azelastine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Azelastine N-Oxide (R)-Isomer can I order?

We supply Azelastine N-Oxide (R)-Isomer in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Azelastine N-Oxide (R)-Isomer?

Yes. Every lot of Azelastine N-Oxide (R)-Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Azelastine N-Oxide (R)-Isomer be shipped internationally?

Yes. Azelastine N-Oxide (R)-Isomer is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.