Avacopan

Name: Avacopan
Brand: Vaqora Chemicals
SKU: VQ-029287

About Avacopan

Vaqora Chemicals supplies Avacopan, a high-purity reference standard of Avacopan registered under CAS number 1346623-17-3. Its molecular formula is C33H35F4N3O2 and its molecular weight is 581.6 g/mol. Common synonyms include CCX-168 and Avacopan (CCX168).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 2 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Avacopan standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Avacopan

View every impurity, metabolite and intermediate we list for Avacopan.

Avacopan impurities

Specifications & identifiers

Chemical identifiers
Product name	Avacopan
Catalogue No.	VQ-029287
CAS Number	1346623-17-3
IUPAC name	(2R,3S)-2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]piperidine-3-carboxamide
Molecular formula	C₃₃H₃₅F₄N₃O₂
Molecular weight	581.6 g/mol
Exact mass	581.2665
Grade	Reference Standard
HSN code	38229090
InChIKey	PUKBOVABABRILL-YZNIXAGQSA-N
SMILES	CC1=C(C(=CC=C1)F)C(=O)N2CCC[C@@H]([C@@H]2C3=CC=C(C=C3)NC4CCCC4)C(=O)NC5=CC(=C(C=C5)C)C(F)(F)F
PubChem CID	49841217

Physical properties
Physical form	Solid
LogP (XLogP3)	7.2
H-bond donors / acceptors	2 / 7
TPSA	61.4 Å²

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Avacopan?

The CAS Registry Number of Avacopan is 1346623-17-3. It is also known as CCX-168, Avacopan (CCX168), EX-A2605.

What is the molecular formula and molecular weight of Avacopan?

Avacopan has the molecular formula C33H35F4N3O2 and a molecular weight of 581.6 g/mol. Its IUPAC name is (2R,3S)-2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]piperidine-3-carboxamide.

What is Avacopan used for?

Avacopan is supplied as a characterised reference material related to Avacopan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Avacopan can I order?

We supply Avacopan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Avacopan?

Yes. Every lot of Avacopan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Avacopan be shipped internationally?

Yes. Avacopan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.