Lamivudine

About Lamivudine

Lamivudine is a high-purity reference standard of Lamivudine carrying the CAS registry number 134678-17-4 at a purity of 99.79%. With the molecular formula C8H11N3O3S, it has a molar mass of 229.26 g/mol. Its systematic (IUPAC) name is 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one. It is also known as (-)-2'-Deoxy-3'-thiacytidine or (-)-BCH 189.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Lamivudine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Lamivudine is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Lamivudine

View every impurity, metabolite and intermediate we list for Lamivudine.

Lamivudine impurities

Specifications & identifiers

Chemical identifiers
Product name	Lamivudine
Catalogue No.	VQ-007523
CAS Number	134678-17-4
IUPAC name	4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
Molecular formula	C₈H₁₁N₃O₃S
Molecular weight	229.26 g/mol
Exact mass	229.0521
Grade	Reference Standard
Purity / assay	99.79%
HSN code	38229090
InChIKey	JTEGQNOMFQHVDC-NKWVEPMBSA-N
SMILES	C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N
PubChem CID	60825

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.9
H-bond donors / acceptors	2 / 4
TPSA	113 Å²
Synonyms	4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone, 4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one, (-)-2'-Deoxy-3'-thiacytidine, (-)-BCH 189, 2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane, cis(-)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane, Epivir, Epivir HBV, Hepitec, Heptodin, Heptovir, Hiviral

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lamivudine?

The CAS Registry Number of Lamivudine is 134678-17-4. It is also known as 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone, 4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one, (-)-2'-Deoxy-3'-thiacytidine.

What is the molecular formula and molecular weight of Lamivudine?

Lamivudine has the molecular formula C8H11N3O3S and a molecular weight of 229.26 g/mol. Its IUPAC name is 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one.

What is Lamivudine used for?

Lamivudine is supplied as a characterised reference material related to Lamivudine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lamivudine can I order?

We supply Lamivudine in Reference Standard (99.79%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lamivudine?

Yes. Every lot of Lamivudine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lamivudine be shipped internationally?

Yes. Lamivudine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.