Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-… 136304-78-4

About Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate

Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate is an impurity of Azilsartan carrying the CAS registry number 136304-78-4. Formula C22H19N3O2, molecular weight 357.4 g/mol. The IUPAC name is methyl 3-amino-2-[[4-(2-cyanophenyl)phenyl]methylamino]benzoate. Common synonyms include Methyl Ester Candersartan Reduzate and Azilsartan pharMaceutical interMediate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Azilsartan impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Azilsartan

View every impurity, metabolite and intermediate we list for Azilsartan.

Azilsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate
Catalogue No.	VQ-029333
CAS Number	136304-78-4
IUPAC name	methyl 3-amino-2-[[4-(2-cyanophenyl)phenyl]methylamino]benzoate
Molecular formula	C₂₂H₁₉N₃O₂
Molecular weight	357.4 g/mol
Exact mass	357.1477
Grade	Reference Standard
HSN code	38229090
InChIKey	LERUETMARSWZRK-UHFFFAOYSA-N
SMILES	COC(=O)C1=C(C(=CC=C1)N)NCC2=CC=C(C=C2)C3=CC=CC=C3C#N
PubChem CID	15654653

Physical properties
Physical form	Solid
LogP (XLogP3)	4.5
H-bond donors / acceptors	2 / 5
TPSA	88.1 Å²
Synonyms	Methyl Ester Candersartan Reduzate, Azilsartan pharMaceutical interMediate, methyl 3-amino-2-[[(2'-cyanobiphenyl-4-yl)methyl]amino]benzoate, Methyl 3-amino-2-{[(2'-cyanobiphenyl-4-yl)methyl]amino}benzoate, methyl 3-amino-2-[(2'-cyanobiphenyl-4-yl)methylamino]benzoate, methyl 3-amino-2-[[(2'-cyanobiphenyi-4-yl)methyl]amino]benzoate, Benzoic acid, 3-amino-2-[[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino]-, methyl ester

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate?

The CAS Registry Number of Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate is 136304-78-4. It is also known as Methyl Ester Candersartan Reduzate, Azilsartan pharMaceutical interMediate, methyl 3-amino-2-[[(2'-cyanobiphenyl-4-yl)methyl]amino]benzoate.

What is the molecular formula and molecular weight of Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate?

Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate has the molecular formula C22H19N3O2 and a molecular weight of 357.4 g/mol. Its IUPAC name is methyl 3-amino-2-[[4-(2-cyanophenyl)phenyl]methylamino]benzoate.

What is Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate used for?

Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate is supplied as a characterised reference material related to Azilsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate can I order?

We supply Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate?

Yes. Every lot of Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate be shipped internationally?

Yes. We export Methyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.