6-Ethyl-5-fluoropyrimidin-4(1H)-one

Name: 6-Ethyl-5-fluoropyrimidin-4(1H)-one
Brand: Vaqora Chemicals
SKU: VQ-013159

About 6-Ethyl-5-fluoropyrimidin-4(1H)-one

6-Ethyl-5-fluoropyrimidin-4(1H)-one (CAS 137234-87-8) is a process intermediate or related compound of Voriconazole offered by Vaqora Chemicals. Formula C6H7FN2O, molecular weight 142.13 g/mol. The IUPAC name is 4-ethyl-5-fluoro-1H-pyrimidin-6-one. Common synonyms include 6-Ethyl-5-fluoropyrimidin-4(3H)-one and 4-Ethyl-5-fluoro-6-hydroxypyrimidine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Voriconazole, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 6-Ethyl-5-fluoropyrimidin-4(1H)-one is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Voriconazole

View every impurity, metabolite and intermediate we list for Voriconazole.

Voriconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Ethyl-5-fluoropyrimidin-4(1H)-one
Catalogue No.	VQ-013159
CAS Number	137234-87-8
IUPAC name	4-ethyl-5-fluoro-1H-pyrimidin-6-one
Molecular formula	C₆H₇FN₂O
Molecular weight	142.13 g/mol
Exact mass	142.0542
Grade	Reference Standard
HSN code	2933
InChIKey	ZEMRCKIJEFNNCO-UHFFFAOYSA-N
SMILES	CCC1=C(C(=O)NC=N1)F
PubChem CID	135405387

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	1 / 3
TPSA	41.5 Å²
Synonyms	6-Ethyl-5-fluoropyrimidin-4(3H)-one, 4-Ethyl-5-fluoro-6-hydroxypyrimidine, 6-Ethyl-5-fluoropyrimidin-4-ol, 6-Ethyl-5-fluoro-4-hydroxypyrimidine, 6-Ethyl-5-fluoro-4(3H)-pyrimidinone, 6-ethyl-5-fluoro-4(3H)-pyrimidone, 6-Ethyl-5-fluoro-pyrimidin-4-ol, 6-ethyl-5-fluoro-1H-pyrimidin-4-one, 4(1H)-Pyrimidinone, 6-ethyl-5-fluoro-, 4(3H)-Pyrimidinone,6-ethyl-5-fluoro-, CS-B1300, 6-ethyl-5-fluoro4-hydroxypyrimidine

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Ethyl-5-fluoropyrimidin-4(1H)-one?

The CAS Registry Number of 6-Ethyl-5-fluoropyrimidin-4(1H)-one is 137234-87-8. It is also known as 6-Ethyl-5-fluoropyrimidin-4(3H)-one, 4-Ethyl-5-fluoro-6-hydroxypyrimidine, 6-Ethyl-5-fluoropyrimidin-4-ol.

What is the molecular formula and molecular weight of 6-Ethyl-5-fluoropyrimidin-4(1H)-one?

6-Ethyl-5-fluoropyrimidin-4(1H)-one has the molecular formula C6H7FN2O and a molecular weight of 142.13 g/mol. Its IUPAC name is 4-ethyl-5-fluoro-1H-pyrimidin-6-one.

What is 6-Ethyl-5-fluoropyrimidin-4(1H)-one used for?

6-Ethyl-5-fluoropyrimidin-4(1H)-one is supplied as a characterised reference material related to Voriconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Ethyl-5-fluoropyrimidin-4(1H)-one can I order?

We supply 6-Ethyl-5-fluoropyrimidin-4(1H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Ethyl-5-fluoropyrimidin-4(1H)-one?

Yes. Every lot of 6-Ethyl-5-fluoropyrimidin-4(1H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Ethyl-5-fluoropyrimidin-4(1H)-one be shipped internationally?

Yes. 6-Ethyl-5-fluoropyrimidin-4(1H)-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.