R-Thiotic Acid Tromethamine

About R-Thiotic Acid Tromethamine

R-Thiotic Acid Tromethamine is an impurity of Thioctic acid carrying the CAS registry number 137314-40-0. Its molecular formula is C12H25NO5S2 and its molecular weight is 327.5 g/mol. Common synonyms include Thioctic acid tromethamine and R-a-Lipoic Acid Tromethamine Salt.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Thioctic acid to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, R-Thiotic Acid Tromethamine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Thioctic acid

View every impurity, metabolite and intermediate we list for Thioctic acid.

Thioctic acid impurities

Specifications & identifiers

Chemical identifiers
Product name	R-Thiotic Acid Tromethamine
Catalogue No.	VQ-034198
CAS Number	137314-40-0
IUPAC name	2-amino-2-(hydroxymethyl)propane-1,3-diol;5-[(3R)-dithiolan-3-yl]pentanoic acid
Molecular formula	C₁₂H₂₅NO₅S₂
Molecular weight	327.5 g/mol
Exact mass	327.1174
Grade	Reference Standard
HSN code	38229090
InChIKey	CCTREOMTIFSZAU-OGFXRTJISA-N
SMILES	C1CSS[C@@H]1CCCCC(=O)O.C(C(CO)(CO)N)O
PubChem CID	9840368

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 8
TPSA	175 Å²
Synonyms	Thioctic acid tromethamine, (R)-5-(1,2-Dithiolaln-3-yl)-pentanoic acid tromethamine, R-a-Lipoic Acid Tromethamine Salt, R-Thioctic Acid Tromethamine, (R)-5-(1,2-dithiolan-3-yl)pentanoic acid 2-amino-2-(hydroxymethyl)propane-1,3-diol salt, R(a)alpha Lipoic acid tromethamine salt, R(, A)Alpha lipoic Acid Tromethamine salt, (R)-Lipoic Acid Tromethamine Salt, R-Thiotic Acid TromethamineQ: What is, R-Thiotic Acid Tromethamine Q: What is the CAS Number of, 2-aminopropane-1,2,3-triol (R)-5-(1,2-dithiolan-3-yl)pentanoate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of R-Thiotic Acid Tromethamine?

The CAS Registry Number of R-Thiotic Acid Tromethamine is 137314-40-0. It is also known as Thioctic acid tromethamine, (R)-5-(1,2-Dithiolaln-3-yl)-pentanoic acid tromethamine, R-a-Lipoic Acid Tromethamine Salt.

What is the molecular formula and molecular weight of R-Thiotic Acid Tromethamine?

R-Thiotic Acid Tromethamine has the molecular formula C12H25NO5S2 and a molecular weight of 327.5 g/mol.

What is R-Thiotic Acid Tromethamine used for?

R-Thiotic Acid Tromethamine is supplied as a characterised reference material related to Thioctic acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of R-Thiotic Acid Tromethamine can I order?

We supply R-Thiotic Acid Tromethamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with R-Thiotic Acid Tromethamine?

Yes. Every lot of R-Thiotic Acid Tromethamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can R-Thiotic Acid Tromethamine be shipped internationally?

Yes. We export R-Thiotic Acid Tromethamine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.