Ezetimibe Diol Impurity

About Ezetimibe Diol Impurity

Ezetimibe Diol Impurity is an impurity of Ezetimibe carrying the CAS registry number 1374250-08-4. Formula C24H25F2NO3, molecular weight 413.5 g/mol. The IUPAC name is (1S,4R)-4-[(S)-(4-fluoroanilino)-(4-hydroxyphenyl)methyl]-1-(4-fluorophenyl)pentane-1,5-diol. Common synonyms include Ezetimibe Diol and Ezetimibe Open-Ring Alcohol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Ezetimibe to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Ezetimibe Diol Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ezetimibe

View every impurity, metabolite and intermediate we list for Ezetimibe.

Ezetimibe impurities

Specifications & identifiers

Chemical identifiers
Product name	Ezetimibe Diol Impurity
Catalogue No.	VQ-004958
CAS Number	1374250-08-4
IUPAC name	(1S,4R)-4-[(S)-(4-fluoroanilino)-(4-hydroxyphenyl)methyl]-1-(4-fluorophenyl)pentane-1,5-diol
Molecular formula	C₂₄H₂₅F₂NO₃
Molecular weight	413.5 g/mol
Exact mass	413.1802
Grade	Reference Standard
HSN code	38229090
InChIKey	MGEXACDCGCPXOT-GKVQRAMASA-N
SMILES	C1=CC(=CC=C1[C@H]([C@@H](CC[C@@H](C2=CC=C(C=C2)F)O)CO)NC3=CC=C(C=C3)F)O
PubChem CID	131873109

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	4 / 6
TPSA	72.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ezetimibe Diol Impurity?

The CAS Registry Number of Ezetimibe Diol Impurity is 1374250-08-4. It is also known as Ezetimibe Diol, Ezetimibe Open-Ring Alcohol, Ezetimibe Diastereomers.

What is the molecular formula and molecular weight of Ezetimibe Diol Impurity?

Ezetimibe Diol Impurity has the molecular formula C24H25F2NO3 and a molecular weight of 413.5 g/mol. Its IUPAC name is (1S,4R)-4-[(S)-(4-fluoroanilino)-(4-hydroxyphenyl)methyl]-1-(4-fluorophenyl)pentane-1,5-diol.

What is Ezetimibe Diol Impurity used for?

Ezetimibe Diol Impurity is supplied as a characterised reference material related to Ezetimibe. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ezetimibe Diol Impurity can I order?

We supply Ezetimibe Diol Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ezetimibe Diol Impurity?

Yes. Every lot of Ezetimibe Diol Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ezetimibe Diol Impurity be shipped internationally?

Yes. We export Ezetimibe Diol Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.