3-Aminohydantoic Acid

About 3-Aminohydantoic Acid

3-Aminohydantoic Acid is an impurity of Nitrofurantoin carrying the CAS registry number 138-07-8. The compound has the formula C3H7N3O3, corresponding to a molecular weight of 133.11 g/mol. Its systematic (IUPAC) name is 2-[amino(carbamoyl)amino]acetic acid. Common synonyms include (1-(Aminocarbonyl)hydrazino)acetic acid and Acetic acid, 2-[1-(aminocarbonyl)hydrazinyl]-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Nitrofurantoin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nitrofurantoin

View every impurity, metabolite and intermediate we list for Nitrofurantoin.

Nitrofurantoin impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Aminohydantoic Acid
Catalogue No.	VQ-038672
CAS Number	138-07-8
IUPAC name	2-[amino(carbamoyl)amino]acetic acid
Molecular formula	C₃H₇N₃O₃
Molecular weight	133.11 g/mol
Exact mass	133.0487
Grade	Reference Standard
HSN code	38229090
InChIKey	WHNSJMMQNFSFBX-UHFFFAOYSA-N
SMILES	C(C(=O)O)N(C(=O)N)N
PubChem CID	67308

Physical properties
Physical form	Solid
LogP (XLogP3)	-4.3
H-bond donors / acceptors	3 / 4
TPSA	110 Å²
Synonyms	(1-(Aminocarbonyl)hydrazino)acetic acid, Acetic acid, 2-[1-(aminocarbonyl)hydrazinyl]-, 2-[1-(Aminocarbonyl)hydrazinyl]acetic acid, 2-(1-carbamoylhydrazin-1-yl)acetic acid, (1-carbamoylhydrazino)acetic acid, 3,6-diaminoglycal, Acetic acid,2-[1-(aminocarbonyl)hydrazinyl]-, N-Amino-N-Carbamoylglycine, 2-(1-Carbamoylhydrazinyl)acetic acid, 2-(Aminoaminocarbonylamino)acetic acid

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Aminohydantoic Acid?

The CAS Registry Number of 3-Aminohydantoic Acid is 138-07-8. It is also known as (1-(Aminocarbonyl)hydrazino)acetic acid, Acetic acid, 2-[1-(aminocarbonyl)hydrazinyl]-, 2-[1-(Aminocarbonyl)hydrazinyl]acetic acid.

What is the molecular formula and molecular weight of 3-Aminohydantoic Acid?

3-Aminohydantoic Acid has the molecular formula C3H7N3O3 and a molecular weight of 133.11 g/mol. Its IUPAC name is 2-[amino(carbamoyl)amino]acetic acid.

What is 3-Aminohydantoic Acid used for?

3-Aminohydantoic Acid is supplied as a characterised reference material related to Nitrofurantoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Aminohydantoic Acid can I order?

We supply 3-Aminohydantoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Aminohydantoic Acid?

Yes. Every lot of 3-Aminohydantoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Aminohydantoic Acid be shipped internationally?

Yes. 3-Aminohydantoic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.