Irbesartan Cyano Impurity

Name: Irbesartan Cyano Impurity
Brand: Vaqora Chemicals
SKU: VQ-022861

About Irbesartan Cyano Impurity

Vaqora Chemicals supplies Irbesartan Cyano Impurity, an impurity of Irbesartan registered under CAS number 138401-24-8. The compound has the formula C25H27N3O, corresponding to a molecular weight of 385.5 g/mol. Its systematic (IUPAC) name is 2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]phenyl]benzonitrile. Common synonyms include Irbesartan Impurity-I and Irbesartan Impurity B.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Irbesartan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Irbesartan Cyano Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Irbesartan

View every impurity, metabolite and intermediate we list for Irbesartan.

Irbesartan impurities

Specifications & identifiers

Chemical identifiers
Product name	Irbesartan Cyano Impurity
Catalogue No.	VQ-022861
CAS Number	138401-24-8
IUPAC name	2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]phenyl]benzonitrile
Molecular formula	C₂₅H₂₇N₃O
Molecular weight	385.5 g/mol
Exact mass	385.2154
Grade	Reference Standard
HSN code	38229090
InChIKey	KWEQEHOPDHARIA-UHFFFAOYSA-N
SMILES	CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C#N
PubChem CID	9843116

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	0 / 3
TPSA	56.5 Å²
Synonyms	Irbesartan Impurity-I, Irbesartan Impurity B, 4'-((2-butyl-4-oxo-1,3-diazaspiro(4.4)non-1-ene-3-yl)methyl)(1,1'-biphenyl)-2-carbonitrile, 4'-((2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-ene-3-yl)methyl)(1,1'-biphenyl)-2-carbonitrile, 4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile, 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]biphenyl-2-carbonitrile, 2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one, 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile, 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl][1,1'-biphenyl]-2-carbonitrile, Irbesartan Impurity 7, 4'-[[2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl]methyl][1,1'-biphenyl]-2-carbonitrile, 2-(n-butyl)-3-[[2'-(cyano)biphenyl-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one

Safety & hazard information (GHS)

Environmental hazard

Signal word: Warning

Hazard statements

H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P273, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Irbesartan Cyano Impurity?

The CAS Registry Number of Irbesartan Cyano Impurity is 138401-24-8. It is also known as Irbesartan Impurity-I, Irbesartan Impurity B, 4'-((2-butyl-4-oxo-1,3-diazaspiro(4.4)non-1-ene-3-yl)methyl)(1,1'-biphenyl)-2-carbonitrile.

What is the molecular formula and molecular weight of Irbesartan Cyano Impurity?

Irbesartan Cyano Impurity has the molecular formula C25H27N3O and a molecular weight of 385.5 g/mol. Its IUPAC name is 2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]phenyl]benzonitrile.

What is Irbesartan Cyano Impurity used for?

Irbesartan Cyano Impurity is supplied as a characterised reference material related to Irbesartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Irbesartan Cyano Impurity can I order?

We supply Irbesartan Cyano Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Irbesartan Cyano Impurity?

Yes. Every lot of Irbesartan Cyano Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Irbesartan Cyano Impurity be shipped internationally?

Yes. Irbesartan Cyano Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.