2-Amino-5-Methyl-3-Thiophenecarbonitrile

Name: 2-Amino-5-Methyl-3-Thiophenecarbonitrile
Brand: Vaqora Chemicals
SKU: VQ-023319

About 2-Amino-5-Methyl-3-Thiophenecarbonitrile

2-Amino-5-Methyl-3-Thiophenecarbonitrile is an impurity of Olanzapine carrying the CAS registry number 138564-58-6. With the molecular formula C6H6N2S, it has a molar mass of 138.19 g/mol. Systematically, it is named 2-amino-5-methylthiophene-3-carbonitrile. Alternative names: 2-Amino-3-cyano-5-methylthiophene and 3-Thiophenecarbonitrile, 2-amino-5-methyl-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 7 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Olanzapine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Amino-5-Methyl-3-Thiophenecarbonitrile in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Olanzapine

View every impurity, metabolite and intermediate we list for Olanzapine.

Olanzapine impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Amino-5-Methyl-3-Thiophenecarbonitrile
Catalogue No.	VQ-023319
CAS Number	138564-58-6
IUPAC name	2-amino-5-methylthiophene-3-carbonitrile
Molecular formula	C₆H₆N₂S
Molecular weight	138.19 g/mol
Exact mass	138.0252
Grade	Reference Standard
HSN code	38229090
InChIKey	YGXADLPRHBRTPG-UHFFFAOYSA-N
SMILES	CC1=CC(=C(S1)N)C#N
PubChem CID	689056

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	1 / 3
TPSA	78.1 Å²
Synonyms	2-Amino-3-cyano-5-methylthiophene, 3-Thiophenecarbonitrile, 2-amino-5-methyl-, 2-Amino-5-methyl-thiophene-3-carbonitrile, 2-amino-5-methyl thiophene-3-carbonitrile, 2-amino-5-methylthiophene3-carbonitrile, 2-amino-5- methylthiophene-3-carbonitrile

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Amino-5-Methyl-3-Thiophenecarbonitrile?

The CAS Registry Number of 2-Amino-5-Methyl-3-Thiophenecarbonitrile is 138564-58-6. It is also known as 2-Amino-3-cyano-5-methylthiophene, 3-Thiophenecarbonitrile, 2-amino-5-methyl-, 2-Amino-5-methyl-thiophene-3-carbonitrile.

What is the molecular formula and molecular weight of 2-Amino-5-Methyl-3-Thiophenecarbonitrile?

2-Amino-5-Methyl-3-Thiophenecarbonitrile has the molecular formula C6H6N2S and a molecular weight of 138.19 g/mol. Its IUPAC name is 2-amino-5-methylthiophene-3-carbonitrile.

What is 2-Amino-5-Methyl-3-Thiophenecarbonitrile used for?

2-Amino-5-Methyl-3-Thiophenecarbonitrile is supplied as a characterised reference material related to Olanzapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Amino-5-Methyl-3-Thiophenecarbonitrile can I order?

We supply 2-Amino-5-Methyl-3-Thiophenecarbonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Amino-5-Methyl-3-Thiophenecarbonitrile?

Yes. Every lot of 2-Amino-5-Methyl-3-Thiophenecarbonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Amino-5-Methyl-3-Thiophenecarbonitrile be shipped internationally?

Yes. 2-Amino-5-Methyl-3-Thiophenecarbonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.