2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butena… 1385789-70-7

About 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide

2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide is a metabolite or degradation product of Teriflunomide carrying the CAS registry number 1385789-70-7. The compound has the formula C12H12N2O2, corresponding to a molecular weight of 216.24 g/mol. Systematically, it is named (E)-2-cyano-3-hydroxy-N-(4-methylphenyl)but-2-enamide. It is also known as 2-Cyano-3-hydroxy-N-(p-tolyl)but-2-enamide.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Teriflunomide, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Teriflunomide

View every impurity, metabolite and intermediate we list for Teriflunomide.

Teriflunomide impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide
Catalogue No.	VQ-022946
CAS Number	1385789-70-7
IUPAC name	(E)-2-cyano-3-hydroxy-N-(4-methylphenyl)but-2-enamide
Molecular formula	C₁₂H₁₂N₂O₂
Molecular weight	216.24 g/mol
Exact mass	216.0899
Grade	Reference Standard
HSN code	38229090
InChIKey	MKTXCGFXIPYXCR-PKNBQFBNSA-N
SMILES	CC1=CC=C(C=C1)NC(=O)/C(=C(\C)/O)/C#N
PubChem CID	70928661

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 3
TPSA	73.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide?

The CAS Registry Number of 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide is 1385789-70-7. It is also known as 2-Cyano-3-hydroxy-N-(p-tolyl)but-2-enamide.

What is the molecular formula and molecular weight of 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide?

2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide has the molecular formula C12H12N2O2 and a molecular weight of 216.24 g/mol. Its IUPAC name is (E)-2-cyano-3-hydroxy-N-(4-methylphenyl)but-2-enamide.

What is 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide used for?

2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide is supplied as a characterised reference material related to Teriflunomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide can I order?

We supply 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide?

Yes. Every lot of 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide be shipped internationally?

Yes. We export 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.