Cobamamide

About Cobamamide

Cobamamide is an impurity of Cyanocobalamin carrying the CAS registry number 13870-90-1. With the molecular formula C72H100CoN18O17P, it has a molar mass of 1579.6 g/mol. Alternative names: Coenzyme B12 and Calomide.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Cyanocobalamin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cyanocobalamin

View every impurity, metabolite and intermediate we list for Cyanocobalamin.

Cyanocobalamin impurities

Specifications & identifiers

Chemical identifiers
Product name	Cobamamide
Catalogue No.	VQ-025103
CAS Number	13870-90-1
IUPAC name	(2S,3S,4R,5R)-2-(6-aminopurin-9-yl)-5-methanidyloxolane-3,4-diol;cobalt(3+);[(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R)-1-[3-[(1R,2R,3R,4Z,7S,9Z,12S,13S,14Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-21-id-3-yl]propanoylamino]propan-2-yl] phosphate
Molecular formula	C₇₂H₁₀₀CoN₁₈O₁₇P
Molecular weight	1579.6 g/mol
Exact mass	1578.6583
Grade	Reference Standard
HSN code	38229090
InChIKey	OAJLVMGLJZXSGX-SLAFOUTOSA-L
PubChem CID	6474320

Physical properties
Physical form	Solid
H-bond donors / acceptors	12 / 27
TPSA	571 Å²
Synonyms	Coenzyme B12, Calomide, adenosylcobalamin, Cobalamine coenzyme, 5'-Deoxyadenosylcobalamine, Vitamin B12 coenzyme

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cobamamide?

The CAS Registry Number of Cobamamide is 13870-90-1. It is also known as Coenzyme B12, Calomide, adenosylcobalamin.

What is the molecular formula and molecular weight of Cobamamide?

Cobamamide has the molecular formula C72H100CoN18O17P and a molecular weight of 1579.6 g/mol.

What is Cobamamide used for?

Cobamamide is supplied as a characterised reference material related to Cyanocobalamin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cobamamide can I order?

We supply Cobamamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cobamamide?

Yes. Every lot of Cobamamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cobamamide be shipped internationally?

Yes. We export Cobamamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.