rac Threo-Dihydro Bupropion Hydrochloride

Name: rac Threo-Dihydro Bupropion Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-044726

About rac Threo-Dihydro Bupropion Hydrochloride

rac Threo-Dihydro Bupropion Hydrochloride (CAS 1396889-62-5) is an impurity of Bupropion offered by Vaqora Chemicals. Formula C13H21Cl2NO, molecular weight 278.21 g/mol. Common synonyms include Bupropion Dihydro Racemate (HCl) and Bupropion Dihydro Racemate (Maleate).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Bupropion impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, rac Threo-Dihydro Bupropion Hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bupropion

View every impurity, metabolite and intermediate we list for Bupropion.

Bupropion impurities

Specifications & identifiers

Chemical identifiers
Product name	rac Threo-Dihydro Bupropion Hydrochloride
Catalogue No.	VQ-044726
CAS Number	1396889-62-5
IUPAC name	(1S,2S)-2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-ol;hydrochloride
Molecular formula	C₁₃H₂₁Cl₂NO
Molecular weight	278.21 g/mol
Exact mass	277.1
Grade	Reference Standard
HSN code	38229090
InChIKey	YZHVQDVGTAELNB-PKKHVXKMSA-N
SMILES	C[C@@H]([C@H](C1=CC(=CC=C1)Cl)O)NC(C)(C)C.Cl
PubChem CID	9878737

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 2
TPSA	32.3 Å²
Synonyms	Bupropion Dihydro Racemate (HCl), Bupropion Dihydro Racemate (Maleate), (1R,2R)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanol hydrochloride, (1R,2R)-1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanol hydrochloride, threo-Dihydro Bupropion Hydrochloride, (S,S)-Dihydro Bupropion Hydrochloride, rac threo-2-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-ol Hydrochloride, Bupropion Dihydro (S,S)-Isomer (HCl)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of rac Threo-Dihydro Bupropion Hydrochloride?

The CAS Registry Number of rac Threo-Dihydro Bupropion Hydrochloride is 1396889-62-5. It is also known as Bupropion Dihydro Racemate (HCl), Bupropion Dihydro Racemate (Maleate), (1R,2R)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanol hydrochloride.

What is the molecular formula and molecular weight of rac Threo-Dihydro Bupropion Hydrochloride?

rac Threo-Dihydro Bupropion Hydrochloride has the molecular formula C13H21Cl2NO and a molecular weight of 278.21 g/mol.

What is rac Threo-Dihydro Bupropion Hydrochloride used for?

rac Threo-Dihydro Bupropion Hydrochloride is supplied as a characterised reference material related to Bupropion. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of rac Threo-Dihydro Bupropion Hydrochloride can I order?

We supply rac Threo-Dihydro Bupropion Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with rac Threo-Dihydro Bupropion Hydrochloride?

Yes. Every lot of rac Threo-Dihydro Bupropion Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can rac Threo-Dihydro Bupropion Hydrochloride be shipped internationally?

Yes. rac Threo-Dihydro Bupropion Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.