Polymyxin B

About Polymyxin B

Polymyxin B is a high-purity reference standard of Polymyxin B carrying the CAS registry number 1404-26-8. Formula C56H98N16O13, molecular weight 1203.5 g/mol. Alternative names: Polimixina B.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Laboratories use this Polymyxin B standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Polymyxin B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Polymyxin B

View every impurity, metabolite and intermediate we list for Polymyxin B.

Polymyxin B impurities

Specifications & identifiers

Chemical identifiers
Product name	Polymyxin B
Catalogue No.	VQ-041547
CAS Number	1404-26-8
IUPAC name	N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18R,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide
Molecular formula	C₅₆H₉₈N₁₆O₁₃
Molecular weight	1203.5 g/mol
Exact mass	1202.7499
Grade	Reference Standard
HSN code	38229090
InChIKey	WQVJHHACXVLGBL-BPJDFBQWSA-N
SMILES	CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)[C@@H](C)O
PubChem CID	49800004

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.5
H-bond donors / acceptors	18 / 18
TPSA	491 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Polymyxin B?

The CAS Registry Number of Polymyxin B is 1404-26-8. It is also known as Polimixina B.

What is the molecular formula and molecular weight of Polymyxin B?

Polymyxin B has the molecular formula C56H98N16O13 and a molecular weight of 1203.5 g/mol.

What is Polymyxin B used for?

Polymyxin B is supplied as a characterised reference material related to Polymyxin B. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Polymyxin B can I order?

We supply Polymyxin B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Polymyxin B?

Yes. Every lot of Polymyxin B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Polymyxin B be shipped internationally?

Yes. Polymyxin B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.