Levosimendan

Name: Levosimendan
Brand: Vaqora Chemicals
SKU: VQ-031539

About Levosimendan

Levosimendan (CAS 141505-33-1) is a high-purity reference standard of Levosimendan offered by Vaqora Chemicals. Formula C14H12N6O, molecular weight 280.28 g/mol. The IUPAC name is 2-[[4-[(4R)-4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl]phenyl]hydrazinylidene]propanedinitrile. Common synonyms include (R)-Simendan and (-)-OR-1259.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Levosimendan, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Levosimendan in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Levosimendan

View every impurity, metabolite and intermediate we list for Levosimendan.

Levosimendan impurities

Specifications & identifiers

Chemical identifiers
Product name	Levosimendan
Catalogue No.	VQ-031539
CAS Number	141505-33-1
IUPAC name	2-[[4-[(4R)-4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl]phenyl]hydrazinylidene]propanedinitrile
Molecular formula	C₁₄H₁₂N₆O
Molecular weight	280.28 g/mol
Exact mass	280.1073
Grade	Reference Standard
HSN code	38229090
InChIKey	WHXMKTBCFHIYNQ-SECBINFHSA-N
SMILES	C[C@@H]1CC(=O)NN=C1C2=CC=C(C=C2)NN=C(C#N)C#N
PubChem CID	3033825

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	2 / 6
TPSA	113 Å²
Synonyms	(R)-Simendan, (-)-OR-1259, Simendan, (r)-, (R)-((4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono) propanedintrile, ({4-[(4R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl]phenyl}hydrazono)propanedintrile, Mesoxalonitrile (p-((R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-pyridazinyl)phenyl)hydrazone, Levosimendan - Bio-X trade mark, [[4-[(4R)-1,4,5,6-Terahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazono]propanedinitrile, 2-[[4-[(4R)-4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl]phenyl]hydrazono]propanedinitrile

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levosimendan?

The CAS Registry Number of Levosimendan is 141505-33-1. It is also known as (R)-Simendan, (-)-OR-1259, Simendan, (r)-.

What is the molecular formula and molecular weight of Levosimendan?

Levosimendan has the molecular formula C14H12N6O and a molecular weight of 280.28 g/mol. Its IUPAC name is 2-[[4-[(4R)-4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl]phenyl]hydrazinylidene]propanedinitrile.

What is Levosimendan used for?

Levosimendan is supplied as a characterised reference material related to Levosimendan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levosimendan can I order?

We supply Levosimendan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levosimendan?

Yes. Every lot of Levosimendan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levosimendan be shipped internationally?

Yes. Levosimendan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.