Prostaglandin A1

About Prostaglandin A1

Prostaglandin A1 is an impurity of Alprostadil carrying the CAS registry number 14152-28-4. Formula C20H32O4, molecular weight 336.5 g/mol. Systematically, it is named 7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanoic acid. Alternative names: 9-oxo-15S-hydroxy-10Z,13E-prostadienoic acid and Prostaglandin E1-217.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Alprostadil, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Prostaglandin A1 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Alprostadil

View every impurity, metabolite and intermediate we list for Alprostadil.

Alprostadil impurities

Specifications & identifiers

Chemical identifiers
Product name	Prostaglandin A1
Catalogue No.	VQ-021512
CAS Number	14152-28-4
IUPAC name	7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanoic acid
Molecular formula	C₂₀H₃₂O₄
Molecular weight	336.5 g/mol
Exact mass	336.2301
Grade	Reference Standard
HSN code	38229090
InChIKey	BGKHCLZFGPIKKU-LDDQNKHRSA-N
SMILES	CCCCC[C@@H](/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O)O
PubChem CID	5281912

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	2 / 4
TPSA	74.6 Å²
Synonyms	9-oxo-15S-hydroxy-10Z,13E-prostadienoic acid, (13E,15S)-15-hydroxy-9-oxo-Prosta-10,13-dien-1-oic acid, 7-((1R,2S)-2-((E,3S)-3-hydroxyoct-1-enyl)-5-oxocyclopent-3-en-1-yl)heptanoic acid, Prosta-10,13-dien-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)-, Prostaglandin E1-217, (13E,15S)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic acid, 15a-Hydroxy-9-oxo-10,13E-prostadienoate, 3-Cyclopentene-1-heptanoic acid, 2-(3-hydroxy-1-octenyl)-5-oxo-, 15-hydroxy-9-oxoprosta-10,13-dienoic acid, 15a-Hydroxy-9-oxo-10,13E-prostadienoic acid, PGA(sub 1)

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P316, P301 + P317, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Prostaglandin A1?

The CAS Registry Number of Prostaglandin A1 is 14152-28-4. It is also known as 9-oxo-15S-hydroxy-10Z,13E-prostadienoic acid, (13E,15S)-15-hydroxy-9-oxo-Prosta-10,13-dien-1-oic acid, 7-((1R,2S)-2-((E,3S)-3-hydroxyoct-1-enyl)-5-oxocyclopent-3-en-1-yl)heptanoic acid.

What is the molecular formula and molecular weight of Prostaglandin A1?

Prostaglandin A1 has the molecular formula C20H32O4 and a molecular weight of 336.5 g/mol. Its IUPAC name is 7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanoic acid.

What is Prostaglandin A1 used for?

Prostaglandin A1 is supplied as a characterised reference material related to Alprostadil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Prostaglandin A1 can I order?

We supply Prostaglandin A1 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Prostaglandin A1?

Yes. Every lot of Prostaglandin A1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Prostaglandin A1 be shipped internationally?

Yes. Prostaglandin A1 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.