Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroi… 1421312-32-4

Name: Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-033684

About Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate

Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate (CAS 1421312-32-4) is a metabolite or degradation product of Roxadustat offered by Vaqora Chemicals. Formula C17H13NO5, molecular weight 311.29 g/mol. Its systematic (IUPAC) name is methyl 4-hydroxy-1-oxo-7-phenoxy-2H-isoquinoline-3-carboxylate. Alternative names: Roxadustat 7-Methyl Ester.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Roxadustat, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Roxadustat

View every impurity, metabolite and intermediate we list for Roxadustat.

Roxadustat impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate
Catalogue No.	VQ-033684
CAS Number	1421312-32-4
IUPAC name	methyl 4-hydroxy-1-oxo-7-phenoxy-2H-isoquinoline-3-carboxylate
Molecular formula	C₁₇H₁₃NO₅
Molecular weight	311.29 g/mol
Exact mass	311.0794
Grade	Reference Standard
HSN code	38229090
InChIKey	WPFRVDGFFDXCKM-UHFFFAOYSA-N
SMILES	COC(=O)C1=C(C2=C(C=C(C=C2)OC3=CC=CC=C3)C(=O)N1)O
PubChem CID	71244894

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 5
TPSA	84.9 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate?

The CAS Registry Number of Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate is 1421312-32-4. It is also known as Roxadustat 7-Methyl Ester, methyl 1,4-dihydroxy-7-phenoxyisoquinoline-3-carboxylate.

What is the molecular formula and molecular weight of Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate?

Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate has the molecular formula C17H13NO5 and a molecular weight of 311.29 g/mol. Its IUPAC name is methyl 4-hydroxy-1-oxo-7-phenoxy-2H-isoquinoline-3-carboxylate.

What is Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate used for?

Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate is supplied as a characterised reference material related to Roxadustat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate can I order?

We supply Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate?

Yes. Every lot of Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate be shipped internationally?

Yes. We export Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.