Rox-8 Methyl Ester Impurity

Name: Rox-8 Methyl Ester Impurity
Brand: Vaqora Chemicals
SKU: VQ-005814

About Rox-8 Methyl Ester Impurity

Listed under CAS 1421312-33-5, Rox-8 Methyl Ester Impurity is an impurity of Roxadustat available from Vaqora Chemicals with a typical assay of 95%. With the molecular formula C17H12ClNO4, it has a molar mass of 329.7 g/mol. Its systematic (IUPAC) name is methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate. Alternative names: Roxadustat Impurity 18 and Roxadustat Impurity N4.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Roxadustat to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Rox-8 Methyl Ester Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Roxadustat

View every impurity, metabolite and intermediate we list for Roxadustat.

Roxadustat impurities

Specifications & identifiers

Chemical identifiers
Product name	Rox-8 Methyl Ester Impurity
Catalogue No.	VQ-005814
CAS Number	1421312-33-5
IUPAC name	methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
Molecular formula	C₁₇H₁₂ClNO₄
Molecular weight	329.7 g/mol
Exact mass	329.0455
Grade	Reference Standard
Purity / assay	95%
HSN code	38229090
InChIKey	UMMWEAOVAUETLR-UHFFFAOYSA-N
SMILES	COC(=O)C1=C(C2=C(C=C(C=C2)OC3=CC=CC=C3)C(=N1)Cl)O
PubChem CID	89400192

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	1 / 5
TPSA	68.7 Å²
Synonyms	Roxadustat Impurity 18, Methyl 1-chloro-4-hydroxy-7-phenoxy-3-isoquinolinecarboxylate, Roxadustat Impurity N4, methyl 1-chloro-4-hydroxy-7-phenoxy-isoquinoline-3-carboxylate, Methyl1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate, 3-Isoquinolinecarboxylic acid, 1-chloro-4-hydroxy-7-phenoxy-, methyl ester

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rox-8 Methyl Ester Impurity?

The CAS Registry Number of Rox-8 Methyl Ester Impurity is 1421312-33-5. It is also known as Roxadustat Impurity 18, Methyl 1-chloro-4-hydroxy-7-phenoxy-3-isoquinolinecarboxylate, Roxadustat Impurity N4.

What is the molecular formula and molecular weight of Rox-8 Methyl Ester Impurity?

Rox-8 Methyl Ester Impurity has the molecular formula C17H12ClNO4 and a molecular weight of 329.7 g/mol. Its IUPAC name is methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate.

What is Rox-8 Methyl Ester Impurity used for?

Rox-8 Methyl Ester Impurity is supplied as a characterised reference material related to Roxadustat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rox-8 Methyl Ester Impurity can I order?

We supply Rox-8 Methyl Ester Impurity in Reference Standard (95%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rox-8 Methyl Ester Impurity?

Yes. Every lot of Rox-8 Methyl Ester Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rox-8 Methyl Ester Impurity be shipped internationally?

Yes. We export Rox-8 Methyl Ester Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.