N,N`-Bis(hydroxyethoxyethyl)piperazine

About N,N`-Bis(hydroxyethoxyethyl)piperazine

N,N`-Bis(hydroxyethoxyethyl)piperazine is a metabolite or degradation product of Quetiapine carrying the CAS registry number 14258-43-6. With the molecular formula C12H26N2O4, it has a molar mass of 262.35 g/mol. Its systematic (IUPAC) name is 2-[2-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]ethoxy]ethanol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Quetiapine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer N,N`-Bis(hydroxyethoxyethyl)piperazine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Quetiapine

View every impurity, metabolite and intermediate we list for Quetiapine.

Quetiapine impurities

Specifications & identifiers

Chemical identifiers
Product name	N,N`-Bis(hydroxyethoxyethyl)piperazine
Catalogue No.	VQ-041789
CAS Number	14258-43-6
IUPAC name	2-[2-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]ethoxy]ethanol
Molecular formula	C₁₂H₂₆N₂O₄
Molecular weight	262.35 g/mol
Exact mass	262.1893
Grade	Reference Standard
HSN code	38229090
InChIKey	XDPJQAWSYBMPOJ-UHFFFAOYSA-N
SMILES	C1CN(CCN1CCOCCO)CCOCCO
PubChem CID	14009070

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.6
H-bond donors / acceptors	2 / 6
TPSA	65.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N,N`-Bis(hydroxyethoxyethyl)piperazine?

The CAS Registry Number of N,N`-Bis(hydroxyethoxyethyl)piperazine is 14258-43-6. It is also known as 2,2'-((piperazine-1,4-diylbis(ethane-2,1-diyl))bis(oxy))diethanol, 2,2a(2)-[1,4-Piperazinediylbis(2,1-ethanediyloxy)]bis[ethanol], 2,2'-{Piperazine-1,4-diylbis[(ethane-2,1-diyl)oxy]}di(ethan-1-ol).

What is the molecular formula and molecular weight of N,N`-Bis(hydroxyethoxyethyl)piperazine?

N,N`-Bis(hydroxyethoxyethyl)piperazine has the molecular formula C12H26N2O4 and a molecular weight of 262.35 g/mol. Its IUPAC name is 2-[2-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]ethoxy]ethanol.

What is N,N`-Bis(hydroxyethoxyethyl)piperazine used for?

N,N`-Bis(hydroxyethoxyethyl)piperazine is supplied as a characterised reference material related to Quetiapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N,N`-Bis(hydroxyethoxyethyl)piperazine can I order?

We supply N,N`-Bis(hydroxyethoxyethyl)piperazine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N,N`-Bis(hydroxyethoxyethyl)piperazine?

Yes. Every lot of N,N`-Bis(hydroxyethoxyethyl)piperazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N,N`-Bis(hydroxyethoxyethyl)piperazine be shipped internationally?

Yes. We export N,N`-Bis(hydroxyethoxyethyl)piperazine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.