3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]… 1428987-67-0

About 3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid

3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid is a metabolite or degradation product of Eltrombopag carrying the CAS registry number 1428987-67-0. The compound has the formula C13H10ClNO3, corresponding to a molecular weight of 263.67 g/mol. Its systematic (IUPAC) name is 3-(3-amino-5-chloro-2-hydroxyphenyl)benzoic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Eltrombopag, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Eltrombopag

View every impurity, metabolite and intermediate we list for Eltrombopag.

Eltrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
Catalogue No.	VQ-048174
CAS Number	1428987-67-0
IUPAC name	3-(3-amino-5-chloro-2-hydroxyphenyl)benzoic acid
Molecular formula	C₁₃H₁₀ClNO₃
Molecular weight	263.67 g/mol
Exact mass	263.0349
Grade	Reference Standard
HSN code	38229090
InChIKey	SKJKBAMFFKMQJF-UHFFFAOYSA-N
SMILES	C1=CC(=CC(=C1)C(=O)O)C2=C(C(=CC(=C2)Cl)N)O
PubChem CID	21072314

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	3 / 4
TPSA	83.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid?

The CAS Registry Number of 3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid is 1428987-67-0. It is also known as (1,1'-Biphenyl)-3-carboxylic acid, 3'-amino-5'-chloro-2'-hydroxy-, [1,1'-Biphenyl]-3-carboxylic acid, 3'-amino-5'-chloro-2'-hydroxy-.

What is the molecular formula and molecular weight of 3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid?

3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid has the molecular formula C13H10ClNO3 and a molecular weight of 263.67 g/mol. Its IUPAC name is 3-(3-amino-5-chloro-2-hydroxyphenyl)benzoic acid.

What is 3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid used for?

3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid is supplied as a characterised reference material related to Eltrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid can I order?

We supply 3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid?

Yes. Every lot of 3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid be shipped internationally?

Yes. We export 3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.