4-Aminopyridine 1-oxide Hydrochloride

About 4-Aminopyridine 1-oxide Hydrochloride

4-Aminopyridine 1-oxide Hydrochloride is a process intermediate or related compound of Dalfampridine carrying the CAS registry number 1433-03-0. Formula C5H7ClN2O, molecular weight 146.57 g/mol. Systematically, it is named 1-hydroxypyridin-4-imine. Hydrochloride. Common synonyms include 4-Aminopyridine 1-oxide monohydrochloride and Pyridin-4-amine 1-oxide hydrochloride.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Dalfampridine, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 4-Aminopyridine 1-oxide Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Dalfampridine

View every impurity, metabolite and intermediate we list for Dalfampridine.

Dalfampridine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Aminopyridine 1-oxide Hydrochloride
Catalogue No.	VQ-013084
CAS Number	1433-03-0
Other CAS	3535-75-9
IUPAC name	1-hydroxypyridin-4-imine;hydrochloride
Molecular formula	C₅H₇ClN₂O
Molecular weight	146.57 g/mol
Exact mass	146.0247
Grade	Reference Standard
HSN code	2933
InChIKey	QNYMQFBKNOARCJ-UHFFFAOYSA-N
SMILES	C1=CN(C=CC1=N)O.Cl
PubChem CID	12257271

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 3
TPSA	47.3 Å²
Synonyms	4-Aminopyridine 1-oxide monohydrochloride, Pyridin-4-amine 1-oxide hydrochloride, 4-Aminopyridine N-oxide hydrochloride, Fampridine N-Oxide Hydrochloride, 4-aminopyridin-1-ium-1-olate hydrochloride, 4-aminopyridin-1-ium-1-olatehydrochloride, 4-Pyridinamine, 1-oxide, hydrochloride (1:?), 4-Iminopyridin-1(4H)-ol--hydrogen chloride (1/1)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Aminopyridine 1-oxide Hydrochloride?

The CAS Registry Number of 4-Aminopyridine 1-oxide Hydrochloride is 1433-03-0. It is also known as 4-Aminopyridine 1-oxide monohydrochloride, Pyridin-4-amine 1-oxide hydrochloride, 4-Aminopyridine N-oxide hydrochloride.

What is the molecular formula and molecular weight of 4-Aminopyridine 1-oxide Hydrochloride?

4-Aminopyridine 1-oxide Hydrochloride has the molecular formula C5H7ClN2O and a molecular weight of 146.57 g/mol.

What is 4-Aminopyridine 1-oxide Hydrochloride used for?

4-Aminopyridine 1-oxide Hydrochloride is supplied as a characterised reference material related to Dalfampridine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Aminopyridine 1-oxide Hydrochloride can I order?

We supply 4-Aminopyridine 1-oxide Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Aminopyridine 1-oxide Hydrochloride?

Yes. Every lot of 4-Aminopyridine 1-oxide Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Aminopyridine 1-oxide Hydrochloride be shipped internationally?

Yes. 4-Aminopyridine 1-oxide Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.