(S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohex… 143415-51-4

Name: (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid
Brand: Vaqora Chemicals
SKU: VQ-044347

About (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid

Listed under CAS 143415-51-4, (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid is an impurity of Carfilzomib available from Vaqora Chemicals. With the molecular formula C15H27NO4, it has a molar mass of 285.38 g/mol. The IUPAC name is (2S)-4-cyclohexyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid. Alternative names: Boc-(S)-2-amino-4-cyclohexylbutanoic acid and Boc-HoCha-OH.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Carfilzomib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Carfilzomib

View every impurity, metabolite and intermediate we list for Carfilzomib.

Carfilzomib impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid
Catalogue No.	VQ-044347
CAS Number	143415-51-4
IUPAC name	(2S)-4-cyclohexyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
Molecular formula	C₁₅H₂₇NO₄
Molecular weight	285.38 g/mol
Exact mass	285.194
Grade	Reference Standard
HSN code	38229090
InChIKey	CMORIBDLPGOGNO-LBPRGKRZSA-N
SMILES	CC(C)(C)OC(=O)N[C@@H](CCC1CCCCC1)C(=O)O
PubChem CID	22862476

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	2 / 4
TPSA	75.6 Å²
Synonyms	(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-cyclohexylbutanoic acid, (2S)-2-(((tert-butoxy)carbonyl)amino)-4-cyclohexylbutanoic acid, Boc-(S)-2-amino-4-cyclohexylbutanoic acid, Boc-HoCha-OH, Boc-HocCha-OH, (S)-2-(Boc-amino)-4-cyclohexylbutanoic Acid, (2S)-t-Butoxycarbonylamino-4-cyclohexylbutanoic acid, (S)-2-tert-butoxycarbonylamino-4-cyclohexyl-butyric acid, (2S)-2-(tert-butoxycarbonylamino)-4-cyclohexyl-butanoic acid, Cyclohexanebutanoic acid, a-[[(1,1-dimethylethoxy)carbonyl]amino]-, (S)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid?

The CAS Registry Number of (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid is 143415-51-4. It is also known as (2S)-2-{[(tert-butoxy)carbonyl]amino}-4-cyclohexylbutanoic acid, (2S)-2-(((tert-butoxy)carbonyl)amino)-4-cyclohexylbutanoic acid, Boc-(S)-2-amino-4-cyclohexylbutanoic acid.

What is the molecular formula and molecular weight of (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid?

(S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid has the molecular formula C15H27NO4 and a molecular weight of 285.38 g/mol. Its IUPAC name is (2S)-4-cyclohexyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid.

What is (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid used for?

(S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid is supplied as a characterised reference material related to Carfilzomib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid can I order?

We supply (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid?

Yes. Every lot of (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid be shipped internationally?

Yes. (S)-2-((tert-Butoxycarbonyl)amino)-4-cyclohexylbutanoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.