(R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol 14347-78-5

About (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol

(R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol is an impurity of Glycerin carrying the CAS registry number 14347-78-5. Its molecular formula is C6H12O3 and its molecular weight is 132.16 g/mol. The IUPAC name is [(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methanol. Alternative names: (R)-Solketal and (R)-(2,2-dimethyl-1,3-dioxolan-4-yl)methanol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Glycerin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Glycerin

View every impurity, metabolite and intermediate we list for Glycerin.

Glycerin impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol
Catalogue No.	VQ-037541
CAS Number	14347-78-5
IUPAC name	[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methanol
Molecular formula	C₆H₁₂O₃
Molecular weight	132.16 g/mol
Exact mass	132.0786
Grade	Reference Standard
HSN code	38229090
InChIKey	RNVYQYLELCKWAN-RXMQYKEDSA-N
SMILES	CC1(OC[C@H](O1)CO)C
PubChem CID	736056

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	1 / 3
TPSA	38.7 Å²
Synonyms	(R)-Solketal, (R)-(2,2-dimethyl-1,3-dioxolan-4-yl)methanol, D-Acetone glycerol, (r)-(-)-1,2-o-isopropylideneglycerol, 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, (R)-, (R)-(-)-(2,2-dimethyl-1,3-dioxolan-4-yl)methanol, ((4R)-2,2-dimethyl-1,3-dioxolan-4-yl)methanol, L-(-)-1,2-Isopropylideneglycerol, r-glycerol acetonide, (R)-glycerol acetonide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H227Combustible liquid
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P210, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol?

The CAS Registry Number of (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol is 14347-78-5. It is also known as (R)-Solketal, (R)-(2,2-dimethyl-1,3-dioxolan-4-yl)methanol, D-Acetone glycerol.

What is the molecular formula and molecular weight of (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol?

(R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol has the molecular formula C6H12O3 and a molecular weight of 132.16 g/mol. Its IUPAC name is [(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methanol.

What is (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol used for?

(R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol is supplied as a characterised reference material related to Glycerin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol can I order?

We supply (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol?

Yes. Every lot of (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol be shipped internationally?

Yes. (R)-(-)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.