Cabazitaxel TSC-4 Impurity

About Cabazitaxel TSC-4 Impurity

Cabazitaxel TSC-4 Impurity is an impurity of Cabazitaxel carrying the CAS registry number 143527-70-2. Its molecular formula is C17H23NO5 and its molecular weight is 321.4 g/mol. The IUPAC name is (4S,5R)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxycarbonyl]-4-phenyl-1,3-oxazolidine-5-carboxylic acid. Common synonyms include Docetaxel Impurity 45.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Cabazitaxel impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cabazitaxel TSC-4 Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cabazitaxel

View every impurity, metabolite and intermediate we list for Cabazitaxel.

Cabazitaxel impurities

Specifications & identifiers

Chemical identifiers
Product name	Cabazitaxel TSC-4 Impurity
Catalogue No.	VQ-004569
CAS Number	143527-70-2
IUPAC name	(4S,5R)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxycarbonyl]-4-phenyl-1,3-oxazolidine-5-carboxylic acid
Molecular formula	C₁₇H₂₃NO₅
Molecular weight	321.4 g/mol
Exact mass	321.1576
Grade	Reference Standard
HSN code	38229090
InChIKey	VAHXMEZCPGHDBJ-QWHCGFSZSA-N
SMILES	CC1(N([C@H]([C@@H](O1)C(=O)O)C2=CC=CC=C2)C(=O)OC(C)(C)C)C
PubChem CID	10969286

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 5
TPSA	76.1 Å²
Synonyms	(4S,5R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic acid, (4S,5R)-5-Carboxy-2,2-dimethyl-4-phenyl-3-(tert-butoxycarbonyl)oxazolidine, (4S,5R)-N-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyl-5-oxazolidinecarboxylic acid, (4S,5R)-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic Acid, (4S,5R)-3-(tBoc)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic Acid, (4S,5R)-3-(tert-butoxycarbonyl)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic acid, Docetaxel Impurity 45, (4S,5R)-3-Boc-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic Acid, (4S,5R)-3-Boc-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic Acid, trans-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid, (4S,5R)-3-[(tert-butoxy)carbonyl]-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic acid, (4S,5R)-3-tert-butoxycarbonyl-2,2-dimethyl-4-phenyl-oxazolidine-5-carboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cabazitaxel TSC-4 Impurity?

The CAS Registry Number of Cabazitaxel TSC-4 Impurity is 143527-70-2. It is also known as (4S,5R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic acid, (4S,5R)-5-Carboxy-2,2-dimethyl-4-phenyl-3-(tert-butoxycarbonyl)oxazolidine, (4S,5R)-N-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyl-5-oxazolidinecarboxylic acid.

What is the molecular formula and molecular weight of Cabazitaxel TSC-4 Impurity?

Cabazitaxel TSC-4 Impurity has the molecular formula C17H23NO5 and a molecular weight of 321.4 g/mol. Its IUPAC name is (4S,5R)-2,2-dimethyl-3-[(2-methylpropan-2-yl)oxycarbonyl]-4-phenyl-1,3-oxazolidine-5-carboxylic acid.

What is Cabazitaxel TSC-4 Impurity used for?

Cabazitaxel TSC-4 Impurity is supplied as a characterised reference material related to Cabazitaxel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cabazitaxel TSC-4 Impurity can I order?

We supply Cabazitaxel TSC-4 Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cabazitaxel TSC-4 Impurity?

Yes. Every lot of Cabazitaxel TSC-4 Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cabazitaxel TSC-4 Impurity be shipped internationally?

Yes. Cabazitaxel TSC-4 Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.