((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate 144163-97-3

About ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate

((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate is an impurity of Ritonavir carrying the CAS registry number 144163-97-3. Its molecular formula is C11H8N2O5S and its molecular weight is 280.26 g/mol. Systematically, it is named (4-nitrophenyl) 1,3-thiazol-5-ylmethyl carbonate. Common synonyms include 4-Nitrophenyl (thiazol-5-ylmethyl) Carbonate and Thiazolylmethyl-4-nitrophenylcarbonate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Ritonavir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ritonavir

View every impurity, metabolite and intermediate we list for Ritonavir.

Ritonavir impurities

Specifications & identifiers

Chemical identifiers
Product name	((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate
Catalogue No.	VQ-025072
CAS Number	144163-97-3
IUPAC name	(4-nitrophenyl) 1,3-thiazol-5-ylmethyl carbonate
Molecular formula	C₁₁H₈N₂O₅S
Molecular weight	280.26 g/mol
Exact mass	280.0154
Grade	Reference Standard
HSN code	38229090
InChIKey	FTEKBGGQRNJIPQ-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1[N+](=O)[O-])OC(=O)OCC2=CN=CS2
PubChem CID	9882147

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	0 / 7
TPSA	122 Å²
Synonyms	4-Nitrophenyl (thiazol-5-ylmethyl) Carbonate, 4-nitrophenyl 1,3-thiazol-5-ylmethyl carbonate, Thiazolylmethyl-4-nitrophenylcarbonate, Carbonic acid, 4-nitrophenyl 5-thiazolylmethyl ester, (4-nitrophenyl) thiazol-5-ylmethyl carbonate, 4-Nitrophenyl (1,3-thiazol-5-yl)methyl carbonate, Carbonic acid 4-Nitrophenyl 5-thiazolylmethyl ester, 4-nitrophenyl thiazol-5-ylmethyl carbonate, 4-Nitrophenyl(thiazol-5-ylmethyl)carbonate, 5-(p-Nitrophenoxycarbonyloxymethyl)thiazole, 5-(p-Nitrophenyoxycarbonyloxymethyl)thiazole

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate?

The CAS Registry Number of ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate is 144163-97-3. It is also known as 4-Nitrophenyl (thiazol-5-ylmethyl) Carbonate, 4-nitrophenyl 1,3-thiazol-5-ylmethyl carbonate, Thiazolylmethyl-4-nitrophenylcarbonate.

What is the molecular formula and molecular weight of ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate?

((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate has the molecular formula C11H8N2O5S and a molecular weight of 280.26 g/mol. Its IUPAC name is (4-nitrophenyl) 1,3-thiazol-5-ylmethyl carbonate.

What is ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate used for?

((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate is supplied as a characterised reference material related to Ritonavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate can I order?

We supply ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate?

Yes. Every lot of ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate be shipped internationally?

Yes. ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.