4-Methylenepiperidine hydrochloride

About 4-Methylenepiperidine hydrochloride

4-Methylenepiperidine hydrochloride is an impurity of Efinaconazole carrying the CAS registry number 144230-50-2. The compound has the formula C6H12ClN, corresponding to a molecular weight of 133.62 g/mol. It is also known as 4-Methylenepiperidine HCl or 4-methylidenepiperidine hydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Efinaconazole impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Methylenepiperidine hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Efinaconazole

View every impurity, metabolite and intermediate we list for Efinaconazole.

Efinaconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Methylenepiperidine hydrochloride
Catalogue No.	VQ-025491
CAS Number	144230-50-2
IUPAC name	4-methylidenepiperidine;hydrochloride
Molecular formula	C₆H₁₂ClN
Molecular weight	133.62 g/mol
Exact mass	133.0658
Grade	Reference Standard
HSN code	38229090
InChIKey	XGMSENVPQPNOHF-UHFFFAOYSA-N
SMILES	C=C1CCNCC1.Cl
PubChem CID	22665826

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 1
TPSA	12 Å²
Synonyms	4-Methylenepiperidine HCl, 4-methylidenepiperidine hydrochloride, Piperidine, 4-methylene-, hydrochloride (1:1), 4-Methylidenepiperidine--hydrogen chloride (1/1), 4-methylidenepiperidine,hydrochloride

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P363, P403 + P233

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Methylenepiperidine hydrochloride?

The CAS Registry Number of 4-Methylenepiperidine hydrochloride is 144230-50-2. It is also known as 4-Methylenepiperidine HCl, 4-methylidenepiperidine hydrochloride, Piperidine, 4-methylene-, hydrochloride (1:1).

What is the molecular formula and molecular weight of 4-Methylenepiperidine hydrochloride?

4-Methylenepiperidine hydrochloride has the molecular formula C6H12ClN and a molecular weight of 133.62 g/mol.

What is 4-Methylenepiperidine hydrochloride used for?

4-Methylenepiperidine hydrochloride is supplied as a characterised reference material related to Efinaconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Methylenepiperidine hydrochloride can I order?

We supply 4-Methylenepiperidine hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Methylenepiperidine hydrochloride?

Yes. Every lot of 4-Methylenepiperidine hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Methylenepiperidine hydrochloride be shipped internationally?

Yes. 4-Methylenepiperidine hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.