Tirofiban

Name: Tirofiban
Brand: Vaqora Chemicals
SKU: VQ-034295

About Tirofiban

Listed under CAS 144494-65-5, Tirofiban is a high-purity reference standard of Tirofiban available from Vaqora Chemicals. With the molecular formula C22H36N2O5S, it has a molar mass of 440.6 g/mol. Systematically, it is named (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid. It is also known as MK-383 or tirofiban hydrochloride (monohydrate).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Tirofiban standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tirofiban

View every impurity, metabolite and intermediate we list for Tirofiban.

Tirofiban impurities

Specifications & identifiers

Chemical identifiers
Product name	Tirofiban
Catalogue No.	VQ-034295
CAS Number	144494-65-5
IUPAC name	(2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid
Molecular formula	C₂₂H₃₆N₂O₅S
Molecular weight	440.6 g/mol
Exact mass	440.2345
Grade	Reference Standard
HSN code	38229090
InChIKey	COKMIXFXJJXBQG-NRFANRHFSA-N
SMILES	CCCCS(=O)(=O)N[C@@H](CC1=CC=C(C=C1)OCCCCC2CCNCC2)C(=O)O
PubChem CID	60947

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	3 / 7
TPSA	113 Å²
Synonyms	N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine, MK-383, (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid, (2S)-2-(butane-1-sulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid, (2S)-2-(butylsulfonylamino)-3-(4-(4-piperidin-4-ylbutoxy)phenyl)propanoic acid, (S)-2-(butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid, N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyrosine, L-Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-, L-Tyrosine, N-(butylsulfonyl)-O-(4-(4-piperidinyl)butyl)-, tirofiban hydrochloride (monohydrate), Tirofiban Hydrochloride Intermediate II

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tirofiban?

The CAS Registry Number of Tirofiban is 144494-65-5. It is also known as N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine, MK-383, (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid.

What is the molecular formula and molecular weight of Tirofiban?

Tirofiban has the molecular formula C22H36N2O5S and a molecular weight of 440.6 g/mol. Its IUPAC name is (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid.

What is Tirofiban used for?

Tirofiban is supplied as a characterised reference material related to Tirofiban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tirofiban can I order?

We supply Tirofiban in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tirofiban?

Yes. Every lot of Tirofiban is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tirofiban be shipped internationally?

Yes. Tirofiban is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.