Linagliptin Impurity E

Name: Linagliptin Impurity E
Brand: Vaqora Chemicals
SKU: VQ-005209

About Linagliptin Impurity E

Listed under CAS 1446263-38-2, Linagliptin Impurity E is an impurity of Linagliptin available from Vaqora Chemicals with a typical assay of 97.86%. With the molecular formula C25H28N8O2, it has a molar mass of 472.5 g/mol. The IUPAC name is 7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-[[(3R)-piperidin-3-yl]amino]purine-2,6-dione. Common synonyms include LIP-2 Regio Isomer and Linagliptine Impurity E.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Linagliptin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Linagliptin Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Linagliptin

View every impurity, metabolite and intermediate we list for Linagliptin.

Linagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Linagliptin Impurity E
Catalogue No.	VQ-005209
CAS Number	1446263-38-2
IUPAC name	7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-[[(3R)-piperidin-3-yl]amino]purine-2,6-dione
Molecular formula	C₂₅H₂₈N₈O₂
Molecular weight	472.5 g/mol
Exact mass	472.2335
Grade	Reference Standard
Purity / assay	97.86%
HSN code	38229090
InChIKey	DOQKYHYFAIBWOA-QGZVFWFLSA-N
SMILES	CC#CCN1C2=C(N=C1N[C@@H]3CCCNC3)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C
PubChem CID	91810488

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	2 / 7
TPSA	108 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Linagliptin Impurity E?

The CAS Registry Number of Linagliptin Impurity E is 1446263-38-2. It is also known as Des-(R)-piperidin-3-amine 8-(R)-(Piperidin-3-ylamino) Linagliptin, LIP-2 Regio Isomer, Linagliptine Impurity E.

What is the molecular formula and molecular weight of Linagliptin Impurity E?

Linagliptin Impurity E has the molecular formula C25H28N8O2 and a molecular weight of 472.5 g/mol. Its IUPAC name is 7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-[[(3R)-piperidin-3-yl]amino]purine-2,6-dione.

What is Linagliptin Impurity E used for?

Linagliptin Impurity E is supplied as a characterised reference material related to Linagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Linagliptin Impurity E can I order?

We supply Linagliptin Impurity E in Reference Standard (97.86%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Linagliptin Impurity E?

Yes. Every lot of Linagliptin Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Linagliptin Impurity E be shipped internationally?

Yes. We export Linagliptin Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.