Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-… 145032-58-2

Name: Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-041635

About Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate

Vaqora Chemicals supplies Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate, an impurity of Pregabalin registered under CAS number 145032-58-2. With the molecular formula C8H10O4, it has a molar mass of 170.16 g/mol. It is also known as Ethyl.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Pregabalin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Pregabalin

View every impurity, metabolite and intermediate we list for Pregabalin.

Pregabalin impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate
Catalogue No.	VQ-041635
CAS Number	145032-58-2
IUPAC name	ethyl (1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate
Molecular formula	C₈H₁₀O₄
Molecular weight	170.16 g/mol
Exact mass	170.0579
Grade	Reference Standard
HSN code	38229090
InChIKey	FZNZMKYHAARKOO-XNCJUZBTSA-N
SMILES	CCOC(=O)[C@]12C[C@H]1COC2=O
PubChem CID	10654701

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	0 / 4
TPSA	52.6 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate?

The CAS Registry Number of Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate is 145032-58-2. It is also known as Ethyl, (1S,5R)-Ethyl 2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate, 3-Oxabicyclo[3.1.0]hexane-1-carboxylic acid, 2-oxo-, ethyl ester, (1S,5R)-.

What is the molecular formula and molecular weight of Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate?

Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate has the molecular formula C8H10O4 and a molecular weight of 170.16 g/mol. Its IUPAC name is ethyl (1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate.

What is Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate used for?

Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate is supplied as a characterised reference material related to Pregabalin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate can I order?

We supply Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate?

Yes. Every lot of Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate be shipped internationally?

Yes. Ethyl(1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.